Associate Professor Joy Wolfram
Associate Professor & Principal Research Fellow
School of Chemical Engineering
Researcher biography
Associate Professor Joy Wolfram leads a extracellular vesicle research program with the goal of developing innovative approaches that bring the next generation of medicines directly to the clinic to alter the trajectory of life-threatening diseases, improve patient outcomes, and prolong healthy lifespan. She has joint appointments in the School of Chemical Engineering and the Australian Institute for Bioengineering and Nanotechnology at The University of Queensland, Australia (#36 in Best Global Universities, U.S. News & World Report).
MISSION
1) Develop a new paradigm of therapeutics (using nanotechnology and cell products) to treat life-threatening diseases that are major causes of death globally, including cardiovascular disease, kidney disease, and breast cancer
2) Save lives by manufacturing at scale - Deliver national manufacturing innovation and a skilled workforce
3) Work with a multidisciplinary team and industry partners to position Australia as a global leader in extracellular vesicle medicine
Extracellular vesicles are small biomolecular packages that are crucial for intercellular communication (locally and systemically). Extracellular vesicles have promising potential to be leveraged and engineered to provide a new paradigm of therapeutics that outperform conventional pharmaceuticals due to versatile bioactive cargo. The Wolfram Laboratory is leveraging innovations in manufacturing, biological mechanisms, and drug loading of extracellular vesicles to develop therapeutics.
FOCUS AREAS
1) Developing improved methods for extracellular vesicle isolation from human biofluids
2) Designing hybrid drug delivery systems with extracellular vesicle and synthetic components for a ‘best-of-both-worlds’ approach to treat cardiovascular disease and aging kidney disease
3) Understanding the role of extracellular vesicles in cancer immunoevasion and metastasis
The research program has resulted in more than 90 publications in journals, such as, Nature Nanotechnology, Materials Today, and Nature Reviews Materials. These publications have been cited 15,600 times (Google Scholar). The Wolfram Laboratory has collaborated with 160 universities and industry partners across 45 countries (Scopus). The research program has also been featured in more than 100 presentations at scientific meetings, including 80+ invited talks and nine international keynote talks.
Associate Professor Wolfram is actively involved in community outreach and education, including her previous roles as the Chair of an education and outreach working group of the National Institutes of Health in the United States and the Associate Program Director of the PhD Program in Regenerative Sciences at Mayo Clinic (Best Hospital in the World, Newsweek). As a TED speaker, she strives to bring science to a wider audience.
She has received 40 awards from eight countries, including the 2016 Amgen Scholars Ten to Watch List (best and brightest up-and-comers in science and medicine across 42 countries), the 2019 Forbes 30 under 30 list in Health Care in the United States/Canada, the 2019 shortlist for the Nature Research Award for Inspiring Science (one of ten worldwide), and the 2021 Finnish Expatriate of the Year (past recipients include Nobel Memorial Prize winners, Millennium Technology Prize winners, and Formula 1 drivers). She is in the top 1% of researchers worldwide in the categories of ‘Biology & Biochemistry’ and ‘Pharmacology & Toxicology' (Essential Science Indicators, 2023) and in the top 0.5% in 'Extracellular Vesicles' (ScholarGPS 5/2024).
Book Chapters
Borsoi, Carlotta, Wolfram, Joy and Ferrari, Mauro (2017). Nanomedicine activities in the United States and worldwide. Nanoscience and nanotechnology for human health. (pp. 21-50) edited by Bert Müller and Marcel Van de Voorde. Weinheim, Germany: Wiley-VCH . doi: 10.1002/9783527692057.ch3
Suri, Krishna, Wolfram, Joy, Shen, Haifa and Ferrari, Mauro (2015). Advances in Nanotechnology-Based Drug Delivery Platforms and Novel Drug Delivery Systems. Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies. (pp. 41-58) Elsevier Inc.. doi: 10.1016/B978-0-12-416603-5.00003-1
Journal Articles
Wolfram, Joy (2024). Extracellular vesicle gatekeepers for tumours. Nature Materials, 1-2. doi: 10.1038/s41563-024-02049-x
Xia, Yutian, Zhang, Jianzhong, Liu, Gang and Wolfram, Joy (2024). Immunogenicity of extracellular vesicles. Advanced Materials, 36 (33) 2403199. doi: 10.1002/adma.202403199
Welsh, Joshua A., Goberdhan, Deborah C. I., O'Driscoll, Lorraine, Buzas, Edit I., Blenkiron, Cherie, Bussolati, Benedetta, Cai, Houjian, Di Vizio, Dolores, Driedonks, Tom A. P., Erdbrugger, Uta, Falcon-Perez, Juan M., Fu, Qing-Ling, Hill, Andrew F., Lenassi, Metka, Lim, Sai Kiang, Mahoney, My G., Mohanty, Sujata, Moller, Andreas, Nieuwland, Rienk, Ochiya, Takahiro, Sahoo, Susmita, Torrecilhas, Ana C., Zheng, Lei, Zijlstra, Andries, Abuelreich, Sarah, Bagabas, Reem, Bergese, Paolo, Bridges, Esther M., Brucale, Marco ... Guanzon, Dominic (2024). Minimal information for studies of extracellular vesicles (MISEV2023): from basic to advanced approaches: Position paper. Journal of Extracellular Vesicles, 13 (2) e12404, 1-84. doi: 10.1002/jev2.12404
Pendiuk Goncalves, Jenifer, Cruz Villarreal, Jorvani, Walker, Sierra A., Tan, Xuan Ning Sharon, Borges, Chad and Wolfram, Joy (2024). High-throughput analysis of glycan sorting into extracellular vesicles. Biochimica et Biophysica Acta. Molecular Cell Research, 1871 (2) 119641. doi: 10.1016/j.bbamcr.2023.119641
Ghebosu, Raluca E., Pendiuk Goncalves, Jenifer and Wolfram, Joy (2023). Extracellular vesicle and lipoprotein interactions. Nano Letters, 24 (1), 1-8. doi: 10.1021/acs.nanolett.3c03579
Iannotta, Dalila, A, Amruta, Kijas, Amanda W., Rowan, Alan E. and Wolfram, Joy (2023). Entry and exit of extracellular vesicles to and from the blood circulation. Nature Nanotechnology, 19 (1), 137-20. doi: 10.1038/s41565-023-01522-z
Iannotta, Dalila, Amruta A., Lai, Andrew, Nair, Soumyalekshmi, Koifman, Na'ama, Lappas, Martha, Salomon, Carlos and Wolfram, Joy (2023). Chemically‐Induced Lipoprotein Breakdown for Improved Extracellular Vesicle Purification. Small, 20 (18) 2307240, 1-14. doi: 10.1002/smll.202307240
Iannotta, Dalila, Goncalves, Jenifer P., Ghebosu, Raluca E., Gopalakrishnan, Aswathi, Cooper-White, Justin and Wolfram, Joy (2023). Transforming undergraduate laboratory courses with interlinked real-world challenges. Trends in Biotechnology, 42 (1), 1-4. doi: 10.1016/j.tibtech.2023.10.006
Amruta, A., Iannotta, Dalila, Cheetham, Seth W., Lammers, Twan and Wolfram, Joy (2023). Vasculature organotropism in drug delivery. Advanced Drug Delivery Reviews, 201 115054, 1-13. doi: 10.1016/j.addr.2023.115054
Chen, Siyu, Iannotta, Dalila, O'Mara, Megan L., Goncalves, Jenifer Pendiuk and Wolfram, Joy (2023). Extracellular vesicle lipids in cancer immunoevasion. Trends in Cancer, 9 (11), 883-886. doi: 10.1016/j.trecan.2023.08.006
Goncalves, Jenifer P., Ghebosu, Raluca E., Tan, Xuan Ning Sharon, Iannotta, Dalila, Koifman, Na'ama and Wolfram, Joy (2023). Hyaluronic acid: An overlooked extracellular vesicle contaminant. Journal of Extracellular Vesicles, 12 (9) 12362, e12362. doi: 10.1002/jev2.12362
Beetler, Danielle J., Bruno, Katelyn A., Watkins, Molly M., Xu, Vivian, Chekuri, Isha, Giresi, Presley, Di Florio, Damian N., Whelan, Emily R., Edenfield, Brandy H., Walker, Sierra A., Morales-Lara, Andrea C., Hill, Anneliese R., Jain, Angita, Auda, Matthew E., Macomb, Logan P., Shapiro, Kathryn A., Keegan, Kevin C., Wolfram, Joy, Behfar, Atta, Stalboerger, Paul G., Terzic, Andre, Farres, Houssam, Cooper, Leslie T. and Fairweather, DeLisa (2023). Reconstituted extracellular vesicles from human platelets decrease viral myocarditis in mice. Small, 19 (49) 2303317, e2303317. doi: 10.1002/smll.202303317
Ghodasara, Aayushi, Raza, Aun, Wolfram, Joy, Salomon, Carlos and Popat, Amirali (2023). Clinical translation of extracellular vesicles. Advanced Healthcare Materials, 12 (28) 2301010, e2301010. doi: 10.1002/adhm.202301010
Pendiuk Goncalves, Jenifer, Walker, Sierra A., Aguilar Díaz de león, Jesús S., Yang, Yubo, Davidovich, Irina, Busatto, Sara, Sarkaria, Jann, Talmon, Yeshayahu, Borges, Chad R. and Wolfram, Joy (2023). Glycan node analysis detects varying glycosaminoglycan levels in melanoma-derived extracellular vesicles. International Journal of Molecular Sciences, 24 (10) 8506, 1-13. doi: 10.3390/ijms24108506
Meneses, Kayleah M., Pandya, Prita, Lindemann, Jennifer A., Al-Qasrawi, Dania S., Argo, Ryan A., Weems, Celeste M., Beetler, Danielle J., Vijay, Geraldine V., Yan, Irene K., Wolfram, Joy, Patel, Tushar and Justilien, Verline (2023). RAB27B drives a cancer stem cell phenotype in NSCLC cells through enhanced extracellular vesicle secretion. Cancer Research Communications, 3 (4), 607-620. doi: 10.1158/2767-9764.crc-22-0425
Bian, Xiaohui, Conley, Sabena M., Eirin, Alfonso, Zimmerman Zuckerman, Eric A., Smith, Anastasia L., Gowan, Cody C., Snow, Zachary K., Jarmi, Tambi, Farres, Houssam, Erben, Young M., Hakaim, Albert G., Dietz, Matthew A., Zubair, Abba C., Wyles, Saranya P., Wolfram, Joy V., Lerman, Lilach O. and Hickson, LaTonya J. (2023). Diabetic kidney disease induces transcriptome alterations associated with angiogenesis activity in human mesenchymal stromal cells. Stem Cell Research and Therapy, 14 (1) 49, 49. doi: 10.1186/s13287-023-03269-9
Broad, Kelly, Walker, Sierra A., Davidovich, Irina, Witwer, Kenneth, Talmon, Yeshayahu and Wolfram, Joy (2023). Unraveling multilayered extracellular vesicles: Speculation on cause. Journal of Extracellular Vesicles, 12 (2) e12309, e12309. doi: 10.1002/jev2.12309
Bruno, Maria Chiara, Cristiano, Maria Chiara, Celia, Christian, d'Avanzo, Nicola, Mancuso, Antonia, Paolino, Donatella, Wolfram, Joy and Fresta, Massimo (2022). Injectable drug delivery systems for osteoarthritis and rheumatoid arthritis. ACS Nano, 16 (12), 19665-19690. doi: 10.1021/acsnano.2c06393
Walker, Sierra A., Davidovich, Irina, Yang, Yubo, Lai, Andrew, Goncalves, Jenifer Pendiuk, Deliwala, Vatsal, Busatto, Sara, Shapiro, Shane, Koifman, Na’ama, Salomon, Carlos, Talmon, Yeshayahu and Wolfram, Joy (2022). Sucrose-based cryoprotective storage of extracellular vesicles. Extracellular Vesicle, 1 100016, 1-7. doi: 10.1016/j.vesic.2022.100016
Beetler, Danielle J., Di Florio, Damian N., Bruno, Katelyn A., Ikezu, Tsuneya, March, Keith L., Cooper, Leslie T., Wolfram, Joy and Fairweather, DeLisa (2022). Extracellular vesicles as personalized medicine. Molecular Aspects of Medicine, 91 101155, 1-14. doi: 10.1016/j.mam.2022.101155
Liskey, Delaney, Cynkin, Laurie and Wolfram, Joy (2022). Patients as biomedical researchers. Trends in Molecular Medicine, 28 (12), 1022-1024. doi: 10.1016/j.molmed.2022.09.002
Goncalves, Jenifer P., Deliwala, Vatsal J., Kolarich, Daniel, Souza-Fonseca-Guimaraes, Fernando and Wolfram, Joy (2022). The cancer cell-derived extracellular vesicle glycocode in immunoevasion. Trends in Immunology, 43 (11), 864-867. doi: 10.1016/j.it.2022.09.004
Busatto, Sara, Yang, Yubo, Iannotta, Dalila, Davidovich, Irina, Talmon, Yeshayahu and Wolfram, Joy (2022). Considerations for extracellular vesicle and lipoprotein interactions in cell culture assays. Journal of Extracellular Vesicles, 11 (4) e12202, e12202. doi: 10.1002/jev2.12202
Yang, Man, Walker, Sierra A., Aguilar Díaz de León, Jesús S., Davidovich, Irina, Broad, Kelly, Talmon, Yeshayahu, Borges, Chad R. and Wolfram, Joy (2022). Extracellular vesicle glucose transporter-1 and glycan features in monocyte-endothelial inflammatory interactions. Nanomedicine, 42 102515, 102515. doi: 10.1016/j.nano.2022.102515
Wang, Xinghua, Pham, Anthony, Kang, Lu, Walker, Sierra A., Davidovich, Irina, Iannotta, Dalila, Terkonda, Sarvam P., Shapiro, Shane, Talmon, Yeshayahu, Pham, Si and Wolfram, Joy (2022). Effects of adipose-derived biogenic nanoparticle-associated microrna-451a on toll-like receptor 4-induced cytokines. Pharmaceutics, 14 (1) 16, 16. doi: 10.3390/pharmaceutics14010016
Iannotta, Dalila, Yang, Man, Celia, Christian, Di Marzio, Luisa and Wolfram, Joy (2021). Extracellular vesicle therapeutics from plasma and adipose tissue. Nano Today, 39 101159, 101159. doi: 10.1016/j.nantod.2021.101159
Busatto, Sara, Iannotta, Dalila, Walker, Sierra A., Di Marzio, Luisa and Wolfram, Joy (2021). A simple and quick method for loading proteins in extracellular vesicles. Pharmaceuticals, 14 (4) 356, 356. doi: 10.3390/ph14040356
Hu, Tony, Wolfram, Joy and Srivastava, Sudhir (2021). Extracellular vesicles in cancer detection: hopes and hypes. Trends in Cancer, 7 (2), 122-133. doi: 10.1016/j.trecan.2020.09.003
Witwer, Kenneth W. and Wolfram, Joy (2021). Extracellular vesicles versus synthetic nanoparticles for drug delivery. Nature Reviews Materials, 6 (2), 103-106. doi: 10.1038/s41578-020-00277-6
Walker, Sierra A., Pham, Anthony, Nizzero, Sara, Kim, Mingee, Riter, Bob, Bletz, Julie, Judge, Sheila, Phillips, Benette, Noble, Dorottya, Murray, Diana, Wetzel, Erin, Samson, Susan, McMahon, Mariah, Flink, Carl, Couch, Jennifer, Tomlin, Claire, Swanson, Kristin, Anderson, Alexander R. A., Odde, David, Shen, Haifa, Hughes, Shannon, Zahir, Nastaran, Enderling, Heiko and Wolfram, Joy (2021). Education and outreach in physical sciences in oncology. Trends in Cancer, 7 (1), 3-9. doi: 10.1016/j.trecan.2020.10.007
Ali, Mojahid, Pham, Anthony, Wang, Xinghua, Wolfram, Joy and Pham, Si (2020). Extracellular vesicles for treatment of solid organ ischemia-reperfusion injury. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 20 (12), 3294-3307. doi: 10.1111/ajt.16164
Busatto, Sara, Yang, Yubo, Walker, Sierra A., Davidovich, Irina, Lin, Wan-Hsin, Lewis-Tuffin, Laura, Anastasiadis, Panagiotis Z., Sarkaria, Jann, Talmon, Yeshayahu, Wurtz, Gregory and Wolfram, Joy (2020). Brain metastases-derived extracellular vesicles induce binding and aggregation of low-density lipoprotein. Journal of Nanobiotechnology, 18 (1) 162, 162. doi: 10.1186/s12951-020-00722-2
Walker, Sierra A., Aguilar Díaz De León, Jesús S., Busatto, Sara, Wurtz, Gregory A., Zubair, Abba C., Borges, Chad R. and Wolfram, Joy (2020). Glycan node analysis of plasma-derived extracellular vesicles. Cells, 9 (9) 5277, 1946-15. doi: 10.3390/cells9091946
Busatto, Sara, Walker, Sierra A., Grayson, Whisper, Pham, Anthony, Tian, Ming, Nesto, Nicole, Barklund, Jacqueline and Wolfram, Joy (2020). Lipoprotein-based drug delivery. Advanced drug delivery reviews, 159, 377-390. doi: 10.1016/j.addr.2020.08.003
Hu, Tony Y., Frieman, Matthew and Wolfram, Joy (2020). Insights from nanomedicine into chloroquine efficacy against COVID-19. Nature Nanotechnology, 15 (4), 247-249. doi: 10.1038/s41565-020-0674-9
Tian, Ming, Ticer, Taylor, Wang, Qikun, Walker, Sierra, Pham, Anthony, Suh, Annie, Busatto, Sara, Davidovich, Irina, Al-Kharboosh, Rawan, Lewis-Tuffin, Laura, Ji, Baoan, Quinones-Hinojosa, Alfredo, Talmon, Yeshayahu, Shapiro, Shane, Rueckert, Felix and Wolfram, Joy (2020). Adipose-derived biogenic nanoparticles for suppression of inflammation. Small, 16 (10) 1904064, 1-13. doi: 10.1002/smll.201904064
Martins, João Pedro, das Neves, José, de la Fuente, María, Celia, Christian, Florindo, Helena, Günday-Türeli, Nazende, Popat, Amirali, Santos, José Luis, Sousa, Flávia, Schmid, Ruth, Wolfram, Joy, Sarmento, Bruno and Santos, Hélder A. (2020). The solid progress of nanomedicine. Drug Delivery and Translational Research, 10 (3), 726-729. doi: 10.1007/s13346-020-00743-2
Walker, Sierra, Busatto, Sara, Pham, Anthony, Tian, Ming, Suh, Annie, Carson, Kelsey, Quintero, Astrid, Lafrence, Maria, Malik, Hanna, Santana, Moises X and Wolfram, Joy (2019). Extracellular vesicle-based drug delivery systems for cancer treatment. Theranostics, 9 (26), 8001-8017. doi: 10.7150/thno.37097
Nizzero, Sara, Li, Feng, Zhang, Guodong, Venuta, Alessandro, Borsoi, Carlotta, Mai, Junhua, Shen, Haifa, Wolfram, Joy, Li, Zheng, Blanco, Elvin and Ferrari, Mauro (2019). Systematic comparison of methods for determining the in vivo biodistribution of porous nanostructured injectable inorganic particles. Acta Biomaterialia, 97, 501-512. doi: 10.1016/j.actbio.2019.08.002
Suh, Annie, Pham, Anthony, Cress, Mikel Jean, Pincelli, Thais, TerKonda, Sarvam P., Bruce, Alison J., Zubair, Abba C., Wolfram, Joy and Shapiro, Shane A. (2019). Adipose-derived cellular and cell-derived regenerative therapies in dermatology and aesthetic rejuvenation. Ageing Research Reviews, 54 100933. doi: 10.1016/j.arr.2019.100933
Leong, Hon S., Butler, Kimberly S., Brinker, C. Jeffrey, Azzawi, May, Conlan, Steve, Dufès, Christine, Owen, Andrew, Rannard, Steve, Scott, Chris, Chen, Chunying, Dobrovolskaia, Marina A., Kozlov, Serguei V., Prina-Mello, Adriele, Schmid, Ruth, Wick, Peter, Caputo, Fanny, Boisseau, Patrick, Crist, Rachael M., McNeil, Scott E., Fadeel, Bengt, Tran, Lang, Hansen, Steffen Foss, Hartmann, Nanna B., Clausen, Lauge P. W., Skjolding, Lars M., Baun, Anders, Ågerstrand, Marlene, Gu, Zhen, Lamprou, Dimitrios A. ... Pastore, Chiara (2019). Publisher Correction: On the issue of transparency and reproducibility in nanomedicine (Nature Nanotechnology, (2019), 14, 7, (629-635), 10.1038/s41565-019-0496-9). Nature Nanotechnology, 14 (9), 902-902. doi: 10.1038/s41565-019-0538-3
Leong, Hon S., Butler, Kimberly S., Brinker, C. Jeffrey, Azzawi, May, Conlan, Steve, Dufès, Christine, Owen, Andrew, Rannard, Steve, Scott, Chris, Chen, Chunying, Dobrovolskaia, Marina A., Kozlov, Serguei V., Prina-Mello, Adriele, Schmid, Ruth, Wick, Peter, Caputo, Fanny, Boisseau, Patrick, Crist, Rachael M., McNeil, Scott E., Fadeel, Bengt, Tran, Lang, Hansen, Steffen Foss, Hartmann, Nanna B., Clausen, Lauge P. W., Skjolding, Lars M., Baun, Anders, Ågerstrand, Marlene, Gu, Zhen, Lamprou, Dimitrios A. ... Pastore, Chiara (2019). Publisher Correction: On the issue of transparency and reproducibility in nanomedicine (Nature Nanotechnology, (2019), 14, 7, (629-635), 10.1038/s41565-019-0496-9). Nature Nanotechnology, 14 (8), 811-811. doi: 10.1038/s41565-019-0523-x
Leong, Hon S., Butler, Kimberly S., Brinker, C. Jeffrey, Azzawi, May, Conlan, Steve, Dufés, Christine, Owen, Andrew, Rannard, Steve, Scott, Chris, Chen, Chunying, Dobrovolskaia, Marina A., Kozlov, Serguei V., Prina-Mello, Adriele, Schmid, Ruth, Wick, Peter, Caputo, Fanny, Boisseau, Patrick, Crist, Rachael M., McNeil, Scott E., Fadeel, Bengt, Tran, Lang, Hansen, Steffen Foss, Hartmann, Nanna B., Clausen, Lauge P. W., Skjolding, Lars M., Baun, Anders, Ågerstrand, Marlene, Gu, Zhen, Lamprou, Dimitrios A. ... Pastore, Chiara (2019). On the issue of transparency and reproducibility in nanomedicine. Nature Nanotechnology, 14 (7), 629-635. doi: 10.1038/s41565-019-0496-9
Busatto, Sara, Pham, Anthony, Suh, Annie, Shapiro, Shane and Wolfram, Joy (2019). Organotropic drug delivery: Synthetic nanoparticles and extracellular vesicles. Biomedical Microdevices, 21 (2) 46, 46. doi: 10.1007/s10544-019-0396-7
Wolfram, Joy and Ferrari, Mauro (2019). Clinical cancer nanomedicine. Nano Today, 25, 85-98. doi: 10.1016/j.nantod.2019.02.005
Busatto, Sara, Vilanilam, George, Ticer, Taylor, Lin, Wen-Lang, Dickson, Dennis, Shapiro, Shane, Bergese, Paolo and Wolfram, Joy (2018). Tangential flow filtration for highly efficient concentration of extracellular vesicles from large volumes of fluid. Cells, 7 (12) 273, 273. doi: 10.3390/cells7120273
Thery, Clotilde, Witwer, Kenneth W., Aikawa, Elena, Jose Alcaraz, Maria, Anderson, Johnathon D., Andriantsitohaina, Ramaroson, Antoniou, Anna, Arab, Tanina, Archer, Fabienne, Atkin-Smith, Georgia K., Ayre, D. Craig, Bach, Jean-Marie, Bachurski, Daniel, Baharvand, Hossein, Balaj, Leonora, Baldacchino, Shawn, Bauer, Natalie N., Baxter, Amy A., Bebawy, Mary, Beckham, Carla, Zavec, Apolonija Bedina, Benmoussa, Abderrahim, Berardi, Anna C., Bergese, Paolo, Bielska, Ewa, Blenkiron, Cherie, Bobis-Wozowicz, Sylwia, Boilard, Eric, Boireau, Wilfrid ... Zuba-Surma, Ewa K. (2018). Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. Journal of Extracellular Vesicles, 7 (1) 1535750, 1535750. doi: 10.1080/20013078.2018.1535750
Pelt, Joe, Busatto, Sara, Ferrari, Mauro, Thompson, E. Aubrey, Mody, Kabir and Wolfram, Joy (2018). Chloroquine and nanoparticle drug delivery: A promising combination. Pharmacology and Therapeutics, 191, 43-49. doi: 10.1016/j.pharmthera.2018.06.007
Mu, Chaofeng, Wu, Xiaoyan, Zhou, Xinyu, Wolfram, Joy, Shen, Jianliang, Zhang, Dechen, Mai, Junhua, Xia, Xiaojun, Holder, Ashley M., Ferrari, Mauro, Liu, Xuewu and Shen, Haifa (2018). Chemotherapy sensitizes therapy-resistant cells to mild hyperthermia by suppressing heat shock protein 27 expression in triple-negative breast cancer. Clinical Cancer Research, 24 (19), 4900-4912. doi: 10.1158/1078-0432.CCR-17-3872
Borrelli, David A., Yankson, Kiera, Shukla, Neha, Vilanilam, George, Ticer, Taylor and Wolfram, Joy (2018). Extracellular vesicle therapeutics for liver disease. Journal of Controlled Release, 273, 86-98. doi: 10.1016/j.jconrel.2018.01.022
Liu, Haoran, Mai, Junhua, Shen, Jianliang, Wolfram, Joy, Li, Zhaoqi, Zhang, Guodong, Xu, Rong, Li, Yan, Mu, Chaofeng, Zu, Youli, Li, Xin, Lokesh, Ganesh L., Thiviyanathan, Varatharasa, Volk, David E., Gorenstein, David G., Ferrari, Mauro, Hu, Zhongbo and Shen, Haifa (2018). A novel DNA aptamer for dual targeting of polymorphonuclear myeloid-derived suppressor cells and tumor cells. Theranostics, 8 (1), 31-44. doi: 10.7150/thno.21342
Wolfram, Joy, Nizzero, Sara, Liu, Haoran, Li, Feng, Zhang, Guodong, Li, Zheng, Shen, Haifa, Blanco, Elvin and Ferrari, Mauro (2017). A chloroquine-induced macrophage-preconditioning strategy for improved nanodelivery. Scientific Reports, 7 (1) 13738. doi: 10.1038/s41598-017-14221-2
Samuelsson, Emma, Shen, Haifa, Blanco, Elvin, Ferrari, Mauro and Wolfram, Joy (2017). Contribution of Kupffer cells to liposome accumulation in the liver. Colloids and Surfaces B: Biointerfaces, 158, 356-362. doi: 10.1016/j.colsurfb.2017.07.014
Khalid, Ayesha, Persano, Stefano, Shen, Haifa, Zhao, Yuliang, Blanco, Elvin, Ferrari, Mauro and Wolfram, Joy (2017). Strategies for improving drug delivery: nanocarriers and microenvironmental priming. Expert Opinion on Drug Delivery, 14 (7), 865-877. doi: 10.1080/17425247.2017.1243527
Shen, Jianliang, Kim, Han-Cheon, Wolfram, Joy, Mu, Chaofeng, Zhang, Wei, Liu, Haoran, Xie, Yan, Mai, Junhua, Zhang, Hang, Li, Zhi, Guevara, Maria, Mao, Zong-Wan and Shen, Haifa (2017). A liposome encapsulated ruthenium polypyridine complex as a theranostic platform for triple-negative breast cancer. Nano Letters, 17 (5), 2913-2920. doi: 10.1021/acs.nanolett.7b00132
Shen, Jianliang, Liu, Haoran, Mu, Chaofeng, Wolfram, Joy, Zhang, Wei, Kim, Han-Cheon, Zhu, Guixian, Hu, Zhongbo, Ji, Liang-Nian, Liu, Xuewu, Ferrari, Mauro, Mao, Zong-Wan and Shen, Haifa (2017). Multi-step encapsulation of chemotherapy and gene silencing agents in functionalized mesoporous silica nanoparticles. Nanoscale, 9 (16), 5329-5341. doi: 10.1039/c7nr00377c
Shen, Jianliang, Wolfram, Joy, Ferrari, Mauro and Shen, Haifa (2017). Taking the vehicle out of drug delivery. Materials Today, 20 (3), 95-97. doi: 10.1016/j.mattod.2017.01.013
Venuta, Alessandro, Wolfram, Joy, Shen, Haifa and Ferrari, Mauro (2017). Post-nano strategies for drug delivery: multistage porous silicon microvectors. Journal of Materials Chemistry B, 5 (2), 207-219. doi: 10.1039/C6TB01978A
Mi, Yu, Wolfram, Joy, Mu, Chaofeng, Liu, Xuewu, Blanco, Elvin, Shen, Haifa and Ferrari, Mauro (2016). Enzyme-responsive multistage vector for drug delivery to tumor tissue. Pharmacological Research, 113, 92-99. doi: 10.1016/j.phrs.2016.08.024
Persano, Stefano, Guevara, Maria L., Wolfram, Joy, Blanco, Elvin, Shen, Haifa, Ferrari, Mauro and Pompa, Pier Paolo (2016). Label-free isothermal amplification assay for specific and highly sensitive colorimetric miRNA detection. ACS Omega, 1 (3), 448-455. doi: 10.1021/acsomega.6b00109
Scott, Bronwyn, Shen, Jianliang, Nizzero, Sara, Boom, Kathryn, Persano, Stefano, Mi, Yu, Liu, Xuewu, Zhao, Yuliang, Blanco, Elvin, Shen, Haifa, Ferrari, Mauro and Wolfram, Joy (2016). A pyruvate decarboxylase-mediated therapeutic strategy for mimicking yeast metabolism in cancer cells. Pharmacological Research, 111, 413-421. doi: 10.1016/j.phrs.2016.07.005
Wolfram, Joy, Scott, Bronwyn, Boom, Kathryn, Shen, Jianliang, Borsoi, Carlotta, Suri, Krishna, Grande, Rossella, Fresta, Massimo, Celia, Christian, Zhao, Yuliang, Shen, Haifa and Ferrari, Mauro (2016). Hesperetin liposomes for cancer therapy. Current Drug Delivery, 13 (5), 711-719. doi: 10.2174/1567201812666151027142412
Mi, Yu, Mu, Chaofeng, Wolfram, Joy, Deng, Zaian, Hu, Tony Ye, Liu, Xuewu, Blanco, Elvin, Shen, Haifa and Ferrari, Mauro (2016). A micro/nano composite for combination treatment of melanoma lung metastasis. Advanced Healthcare Materials, 5 (8), 936-946. doi: 10.1002/adhm.201500910
Wolfram, Joy, Shen, Haifa and Ferrari, Mauro (2015). Multistage vector (MSV) therapeutics. Journal of Controlled Release, 219, 406-415. doi: 10.1016/j.jconrel.2015.08.010
Scavo, Maria Principia, Gentile, Emanuela, Wolfram, Joy, Gu, Jianhua, Barone, Michele, Evangelopoulos, Michael, Martinez, Jonathan O., Liu, Xuewu, Celia, Christian, Tasciotti, Ennio, Vilar, Eduardo and Shen, Haifa (2015). Multistage vector delivery of sulindac and silymarin for prevention of colon cancer. Colloids and Surfaces B: Biointerfaces, 136, 694-703. doi: 10.1016/j.colsurfb.2015.10.005
Khalid, Ayesha, Wolfram, Joy, Ferrari, Ilaria, Mu, Chaofeng, Mai, Junhua, Yang, Zhizhou, Zhao, Yuliang, Ferrari, Mauro, Ma, Xiaojing and Shen, Haifa (2015). Recent advances in discovering the role of CCL5 in metastatic breast cancer. Mini-Reviews in Medicinal Chemistry, 15 (13), 1063-1072. doi: 10.2174/138955751513150923094709
Yang, Zhizhou, Sun, Zhaorui, Liu, Hongmei, Ren, Yi, Shao, Danbing, Zhang, Wei, Lin, Jinfeng, Wolfram, Joy, Wang, Feng and Nie, Shinan (2015). Connective tissue growth factor stimulates the proliferation, migration and differentiation of lung fibroblasts during paraquat-induced pulmonary fibrosis. Molecular Medicine Reports, 12 (1), 1091-1097. doi: 10.3892/mmr.2015.3537
Lin, Jinfeng, Sun, Zhaorui, Zhang, Wei, Liu, Hongmei, Shao, Danbing, Ren, Yi, Wen, Yanfang, Cao, Liping, Wolfram, Joy, Yang, Zhizhou and Nie, Shinan (2015). Protective effects of intestinal trefoil factor (ITF) on gastric mucosal epithelium through activation of extracellular signal-regulated kinase 1/2 (ERK1/2). Molecular and Cellular Biochemistry: an international journal for chemical biology in health and disease, 404 (1-2), 263-270. doi: 10.1007/s11010-015-2386-2
Pasut, Gianfranco, Paolino, Donatella, Celia, Christian, Mero, Anna, Joseph, Adrian Steve, Wolfram, Joy, Cosco, Donato, Schiavon, Oddone, Shen, Haifa and Fresta, Massimo (2015). Polyethylene glycol (PEG)-dendron phospholipids as innovative constructs for the preparation of super stealth liposomes for anticancer therapy. Journal of Controlled Release, 199, 106-113. doi: 10.1016/j.jconrel.2014.12.008
Shen, Jianliang, Wu, Xiaoyan, Lee, Yeonju, Wolfram, Joy, Yang, Zhizhou, Mao, Zong-Wan, Ferrari, Mauro and Shen, Haifa (2015). Porous silicon microparticles for delivery of siRNA therapeutics. Journal of Visualized Experiments (95) e52075. doi: 10.3791/52075
Wolfram, Joy, Zhu, Motao, Yang, Yong, Shen, Jianliang, Gentile, Emanuela, Paolino, Donatella, Fresta, Massimo, Nie, Guangjun, Chen, Chunying, Shen, Haifa, Ferrari, Mauro and Zhao, Yuliang (2015). Safety of nanoparticles in medicine. Current Drug Targets, 16 (14), 1671-1681. doi: 10.2174/1389450115666140804124808
Wolfram, Joy, Yang, Yong, Shen, Jianliang, Moten, Asad, Chen, Chunying, Shen, Haifa, Ferrari, Mauro and Zhao, Yuliang (2014). The nano-plasma interface: Implications of the protein corona. Colloids and Surfaces B: Biointerfaces, 124, 17-24. doi: 10.1016/j.colsurfb.2014.02.035
Shen, Jianliang, Kim, Han-Cheon, Mu, Chaofeng, Gentile, Emanuela, Mai, Junhua, Wolfram, Joy, Ji, Liang-Nian, Ferrari, Mauro, Mao, Zong-wan and Shen, Haifa (2014). Multifunctional gold nanorods for siRNA gene silencing and photothermal therapy. Advanced Healthcare Materials, 3 (10), 1629-1637. doi: 10.1002/adhm.201400103
Jiang, Xionghua, Chen, Zhenxing, Wolfram, Joy, Wei, Zhongxian, Shen, Yuqiu and Yang, Zhizhou (2014). The impact of lubricants on the precision lapping process. Microscopy and Microanalysis, 20 (6), 1708-1714. doi: 10.1017/S1431927614013397
Yang, Yong, Wolfram, Joy, Fang, Xiaohong, Shen, Haifa and Ferrari, Mauro (2014). Polyarginine induces an antitumor immune response through binding to toll-like receptor 4. Small, 10 (7), 1250-1254. doi: 10.1002/smll.201302887
Wolfram, Joy, Suri, Krishna, Yang, Yong, Shen, Jianliang, Celia, Christian, Fresta, Massimo, Zhao, Yuliang, Shen, Haifa and Ferrari, Mauro (2014). Shrinkage of pegylated and non-pegylated liposomes in serum. Colloids and Surfaces B: Biointerfaces, 114, 294-300. doi: 10.1016/j.colsurfb.2013.10.009
Rauhamäki, Virve, Wolfram, Joy, Jokitalo, Eija, Hanski, Ilkka and Dahlhoff, Elizabeth P. (2014). Differences in the aerobic capacity of flight muscles between butterfly populations and species with dissimilar flight abilities. PLoS ONE, 9 (1) e78069, e78069. doi: 10.1371/journal.pone.0078069
Paolino, Donatella, Cosco, Donato, Gaspari, Marco, Celano, Marilena, Wolfram, Joy, Voce, Pasquale, Puxeddu, Efisio, Filetti, Sebastiano, Celia, Christian, Ferrari, Mauro, Russo, Diego and Fresta, Massimo (2014). Targeting the thyroid gland with thyroid-stimulating hormone (TSH)-nanoliposomes. Biomaterials, 35 (25), 7101-7109. doi: 10.1016/j.biomaterials.2014.04.088
Shen, Jianliang, Kim, Han-Cheon, Su, Hua, Wang, Feng, Wolfram, Joy, Kirui, Dickson, Mai, Junhua, Mu, Chaofeng, Ji, Liang-Nian, Mao, Zong-Wan and Shen, Haifa (2014). Cyclodextrin and polyethylenimine functionalized mesoporous silica nanoparticles for delivery of siRNA cancer therapeutics. Theranostics, 4 (5), 487-497. doi: 10.7150/thno.8263
Wolfram, Joy, Suri, Krishna, Huang, Yi, Molinaro, Roberto, Borsoi, Carlotta, Scott, Bronwyn, Boom, Kathryn, Paolino, Donatella, Fresta, Massimo, Wang, Jianghua, Ferrari, Mauro, Celia, Christian and Shen, Haifa (2014). Evaluation of anticancer activity of celastrol liposomes in prostate cancer cells. Journal of Microencapsulation, 31 (5), 501-507. doi: 10.3109/02652048.2013.879932
Jiang, Xionghua, Chen, Zhenxing, Wolfram, Joy and Yang, Zhizhou (2014). Mechanistic features of nanodiamonds in the lapping of magnetic heads. Scientific World Journal, 2014 326427. doi: 10.1155/2014/326427
Wolfram, Joy, Zhu, Motao, Yang, Yong, Shen, Jianliang, Gentile, Emanuela, Paolino, Donatella, Fresta, Massimo, Nie, Guangjun, Chen, Chunying, Shen, Haifa, Ferrari, Mauro and Zhao, Yuliang (2014). Safety of nanoparticles in medicine. Current Drug Targets, 15 (10) A001.
Yang, Yong, Wolfram, Joy, Shen, Jianliang, Zhao, Yuliang, Fang, Xiaohong, Shen, Haifa and Ferrari, Mauro (2013). Live-cell single-molecule imaging reveals clathrin and caveolin-1 dependent docking of SMAD4 at the cell membrane. FEBS Letters, 587 (24), 3912-3920. doi: 10.1016/j.febslet.2013.10.041
Celia, Christian, Trapasso, Elena, Locatelli, Marcello, Navarra, Michele, Ventura, Cinzia Anna, Wolfram, Joy, Carafa, Maria, Morittu, Valeria Maria, Britti, Domenico, Di Marzio, Luisa and Paolino, Donatella (2013). Anticancer activity of liposomal bergamot essential oil (BEO) on human neuroblastoma cells. Colloids and Surfaces B: Biointerfaces, 112, 548-553. doi: 10.1016/j.colsurfb.2013.09.017
Gentile, Emanuela, Cilurzo, Felisa, Di Marzio, Luisa, Carafa, Maria, Ventura, Cinzia Anna, Wolfram, Joy, Paolino, Donatella and Celia, Christian (2013). Liposomal chemotherapeutics. Future Oncology, 9 (12), 1849-1859. doi: 10.2217/FON.13.146
Shen, Jianliang, Xu, Rong, Mai, Junhua, Kim, Han-Cheon, Guo, Xiaojing, Qin, Guoting, Yang, Yong, Wolfram, Joy, Mu, Chaofeng, Xia, Xiaojun, Gu, Jianhua, Liu, Xuewu, Mao, Zong-Wan, Ferrari, Mauro and Shen, Haifa (2013). High capacity nanoporous silicon carrier for systemic delivery of gene silencing therapeutics. ACS Nano, 7 (11), 9867-9880. doi: 10.1021/nn4035316
Yang, Yong, Wolfram, Joy, Boom, Kathryn, Fang, Xiaohong, Shen, Haifa and Ferrari, Mauro (2013). Hesperetin impairs glucose uptake and inhibits proliferation of breast cancer cells. Cell Biochemistry and Function, 31 (5), 374-379. doi: 10.1002/cbf.2905
Molinaro, Roberto, Wolfram, Joy, Federico, Cinzia, Cilurzo, Felisa, Di Marzio, Luisa, Ventura, Cinzia A., Carafa, Maria, Celia, Christian and Fresta, Massimo (2013). Polyethylenimine and chitosan carriers for the delivery of RNA interference effectors. Expert Opinion on Drug Delivery, 10 (12), 1653-1668. doi: 10.1517/17425247.2013.840286
Yang, Yong, Wolfram, Joy, Shen, Haifa, Fang, Xiaohong and Ferrari, Mauro (2012). Hesperetin: An inhibitor of the transforming growth factor-β (TGF-β) signaling pathway. European Journal of Medicinal Chemistry, 58, 390-395. doi: 10.1016/j.ejmech.2012.10.028
Conference Papers
Wolfram, Joy (2024). Engineering medicines with nature’s blueprint. The University of Queensland School of Chemical Engineering Seminar Series, Brisbane, QLD, Australia, 18 September 2024.
Wolfram, Joy (2024). Next-generation extracellular vesicles in medicine. Olivia Newton-John Cancer Research Institute Seminar Series, Heidelberg, Victoria, Australia, 16 September 2024.
Wolfram, Joy (2024). Extracellular vesicles as a new paradigm of therapeutics. Monash University Department of Chemical and Biological Engineering Platinum Seminar Series, Melbourne, VIC, Australia, 21 August 2024.
Wolfram, Joy (2024). Extracellular vesicles as a new paradigm of therapeutics. The University of Queensland Symposium on Extracellular Vesicles in Neurodegenerative Diseases, Brisbane, QLD, Australia, 13 May 2024.
Wolfram, Joy (2023). The extracellular vesicle glycocode in breast cancer. Brisbane Cancer Conference, Brisbane, QLD, Australia, 23-24 November 2023.
Wolfram, Joy (2023). Next-generation extracellular vesicle therapeutics. World Laureates Forum, Shanghai, China, 5-7 November 2023.
Wolfram, Joy (2023). Next-generation extracellular vesicle therapeutics for cardiovascular disease. Tissue Engineering and Regenerative Medicine International Society Asia-Pacific (TERMIS-AP), Hong Kong, 16-19 October 2023.
Wolfram, Joy (2023). Next-generation extracellular vesicle therapeutics. Hudson Institute of Medical Research Seminar Series, Melbourne, VIC, Australia, 31 August 2023.
Wolfram, Joy (2023). Next-generation extracellular vesicle therapeutics. Srust 1st CoA Career Advancing Nanomedicine, Japan (virtual), 29 August 2023.
Beetler, Danielle, Bruno, Katelyn, Wolfram, Joy and Fairweather, DeLisa (2023). Myocarditis treatments within our sights: targeting inflammatory conversations In the heart using extracellular vesicles. American Heart Association's Basic Cardiovascular Sciences Scientific Sessions 2023: Innovations and Discovery in Cardiovascular Science, Boston, MA, United States, 31 July-3 August 2023. Philadelphia, PA, United States: Lippincott Williams & Wilkins. doi: 10.1161/res.133.suppl_1.p3160
Wolfram, Joy (2023). Extracellular vesicles for mRNA delivery. Queensland mRNA Symposium, Brisbane, Australia, 14 July 2023.
Wolfram, Joy (2023). Next-generation extracellular vesicles in medicine. Graeme Clark Institute Seminar Series, Melbourne, VIC, Australia, 28 June 2023.
Meneses, Kayleah M., Lindemann, Jennifer A., Pandya, Prita, Al-Qasrawi, Dania S., Argo, Ryan, Weems, Celeste, Beetler, Danielle J., Yan, Irene K., Wolfram, Joy, Patel, Tushar C. and Justilien, Verline (2023). Abstract 2444: RAB27B drives a cancer stem cell phenotype in non-small cell lung cancer cells through enhanced extracellular vesicle secretion. AACR Annual Meeting 2023, Orlando, FL United States, 14-19 April 2023. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2023-2444
Wolfram, Joy (2023). Extracellular vesicle therapeutics for cardiovascular disease. The University of Queensland Cardiac and Vascular Biology Symposium, Brisbane, QLD, Australia, 2 February 2023.
Wolfram, Joy (2022). The extracellular vesicle glyco-code. Multi-Omics, Brisbane, Queensland, Australia , December 2022.
Wolfram, Joy (2022). The glycome: the missing link in extracellular vesicle research. 4th Australasian Glycoscience Symposium, Gold Coast, QLD, Australia , November 2022.
Wolfram, Joy (2022). Extracellular vesicle therapeutics for treating inflammatory conditions. Australia and New Zealand Society for Extracellular Vesicles Annual Meeting, Gold Coast, QLD, Australia , November 2022.
Iannotta, Dalila, Busatto, Sara, Yang, Yubo, Davidovich, Irina, Talmon, Yeshayahu and Wolfram, Joy (2022). Consideration for extracellular vesicle and lipoprotein interactions in cell culture assays. Australia and New Zealand Society for Extracellular Vesicles Annual Meeting, Gold Coast, QLD, Australia , 9-11 November 2022.
Wolfram, Joy (2022). Extracellular vesicle technology for regenerative therapy. Mayo Clinic Regenerative Nephrology and Kidney Transplantation Conference, Jacksonville, FL, United States , October 2022.
Pastorin, Giorgia, Neupane, Yup, Chenyuan, Huang, Chng, Wei Heng, Lee, Choon, Wang, Jiong Wei and Wolfram, Joy (2022). Cardioprotective activity of bioinspired cell-derived nanovesicles.. Tissue Engineering and Regenerative Medicine International Society Asia-Pacific (TERMIS-AP), Jeju, South Korea , October 2022. NEW ROCHELLE: MARY ANN LIEBERT, INC.
Wolfram, Joy (2022). Extracellular vesicles for therapeutic and diagnostic applications. Griffith University Institute for Drug Discovery Seminar Series, Nathan, QLD, Australia , October 2022.
Wolfram, Joy (2022). Extracellular vesicle therapeutics for treating inflammatory conditions. Tissue Engineering and Regenerative Medicine International Society Asia-Pacific (TERMIS-AP), Jeju, South Korea , October 2022.
Wolfram, Joy (2022). Extracellular vesicles for therapeutic and diagnostic applications. The University of Queensland School of Pharmacy Seminar Series, Brisbane, QLD, Australia , June 2022.
Wolfram, Joy (2022). Extracellular vesicles for therapeutic and diagnostic applications. QIMR Berghofer Medical Research Institute Cancer Research Program Seminar Series, Brisbane, QLD, Australia , June 2022.
Wolfram, Joy (2022). Therapeutic extracellular vesicles for treating inflammatory conditions. Allogeneic Stem Cell Manufacturing (ASTEM) Seminar Series, Singapore, June 2022.
Wolfram, Joy (2022). Extracellular vesicles for therapeutic and diagnostic applications. Griffith University Institute for Glycomics Seminar Series, Gold Coast, QLD, Australia , June 2022.
Wolfram, Joy (2022). Extracellular vesicles for therapeutic and diagnostic applications. Wenzhou Institute University of Chinese Academy of Sciences Seminar Series, Wenzhou, China [virtual] , June 2022.
Wolfram, Joy (2022). Missing in EV technology: fat, sugar, and ice. Australia and New Zealand Society for Extracellular Vesicles Extracellular Vesicle Technology Mini-Symposium, Australia/New Zealand [virtual] , May 2022.
Wolfram, Joy (2022). Extracellular vesicles for therapeutic and diagnostic applications. Queensland University of Technology Centre for Biomedical Technologies Seminar Series, Brisbane, QLD, Australia, May 2022.
Wolfram, Joy (2022). Therapeutic extracellular vesicles for treating inflammatory conditions (rapid talk). A*STAR Advances in Cell and Gene Therapy Symposium, Singapore [virtual] , May 2022.
Wolfram, Joy (2022). Extracellular vesicles for therapeutic and diagnostic applications. The University of Queensland Institute for Molecular Bioscience Seminar Series, Brisbane, QLD, Australia , April 2022.
Wolfram, Joy (2022). Extracellular vesicles for therapeutic and diagnostic applications. Australian Institute for Bioengineering and Nanotechnology Seminar Series, Brisbane, QLD, Australia , February 2022.
Wolfram, Joy (2022). Therapeutic and diagnostic extracellular vesicles for inflammatory diseases and cancer. The 2nd K-DOC Science Online Conference hosted by the National Research Foundation of Korea, Seoul, Korea [virtual], January 2022.
Wolfram, Joy (2021). Extracellular vesicles in medicine. World Laureates Forum, Shanghai, China [virtual] , November 2021.
Wolfram, Joy (2021). Extracellular vesicles for therapeutic and diagnostic applications. Universidad Iberoamericana Seminar Series, Santo Domingo, Dominican Republic [virtual] , November 2021.
Xu, Vivian, Beetler, Danielle, Di Florio, Damian, Bruno, Katelyn, Wolfram, Joy and Fairweather, DeLisa (2021). Adipose nanomedicine treatment in vivo – injecting nanoparticles for alleviating acute myocarditis. Annual Biomedical Research Conference for Minority Students, United States [virtual] , November 2021.
Wolfram, Joy (2021). Extracellular vesicles for therapeutic and diagnostic applications. Mayo Clinic Research Fellow’s Association Seminar Series, Rochester, MN, United States [virtual] , October 2021.
Wolfram, Joy (2021). Extracellular vesicles for therapeutic and diagnostic applications. Summer School on Molecular Imaging, Madrid, Spain [virtual] , September 2021.
Wolfram, Joy (2021). Education and outreach unit of the center for immunotherapeutic transport oncophysics. National Cancer Institute Physical Sciences-Oncology Steering Committee Meeting, National Institutes of Health, Bethesda, MD, United States [virtual] , September 2021.
Wolfram, Joy (2021). Extracellular vesicle therapeutics and diagnostics. WebEV, Global [virtual], August 2021.
Wolfram, Joy (2021). Extracellular vesicle therapeutics: from past to present. American Society of Biochemistry and Molecular Biology, United States , July 2021.
Wolfram, Joy (2021). From petri dishes to big wishes. University of Helsinki International Research Networking, Helsinki, Finland [virtual] , June 2021.
Conley, S. M., Bian, X., Gowan, C. C., Snow, Z. K., Smith, A. L., Lerman, L., Wolfram, J. V., Zubair, A. and Hickson, L. (2021). SYSTEMIC DELIVERY OF HUMAN BONE-MARROW DERIVED EXTRACELLULAR VESICLES AMELIORATES KIDNEY INJURY AND INFLAMMATION IN AN ACCELERATED DIABETIC KIDNEY DISEASE MOUSE MODEL. OXFORD: ELSEVIER SCI LTD.
Conley, S.M., Bian, X., C. Gowan, C., Snow, Z.K., Smith, A.L., Lerman, L., Wolfram, J.V., Zubair, A. and Hickson, L. (2021). Systemic delivery of human bone-marrow derived extracellular vesicles ameliorates kidney injury and inflammation in an accelerated diabetic kidney disease mouse model. 27th Annual ISCT Meeting, Online, 25 - 28 May 2021. Oxford, United Kingdom: Elsevier. doi: 10.1016/s1465324921004448
Wolfram, Joy (2021). Therapeutic and diagnostic applications of extracellular vesicles in cancer. The First International Biomedical Academic Forum of Youjiang Medical University for Nationalities, Baise, Guangxi, China [virtual] , May 2021.
Wolfram, Joy (2021). Extracellular vesicles in cancer. Oxford Global Pharmatest Webinar, Global [virtual] , May 2021.
Wolfram, Joy (2021). Extracellular vesicles for therapeutic and diagnostic applications. The Ohio State University Biomedical Engineering Seminar Series, Columbus, OH, United States [virtual] , March 2021.
Wolfram, Joy (2020). Extracellular vesicles in medicine. World Laureates Forum, Shanghai, China [virtual] , October 2020.
Wolfram, Joy (2020). Therapeutic and diagnostic use of extracellular vesicles. University of Florida Infectious Diseases and Immunology Seminar Series, Gainesville, FL USA/Virtual, September 2020.
Iannotta, Dalila, Celia, Christian , Wolfram, Joy, Agata, P. and Di Marzio, Luisa (2020). Discoidal nanoparticles: reaction environment-dependent size response. NanoInnovation 2020, Rome, Italy , September 2020.
Wolfram, Joy (2020). Extracellular vesicle therapeutics. University of North Carolina at Chapel Hill Rising Stars in Drug Delivery Seminar Series, Chapel Hill, NC USA/Virtual, July 2020.
Wolfram, Joy (2020). Extracellular vesicle therapeutics. City University of New York Converge to Transform, New York City, NY, United States, June 2020.
Wolfram, Joy (2020). Education and Outreach Unit. National Cancer Institute Physical Sciences-Oncology Network Site Visit, Houston, TX USA/Virtual, April 2020.
Wolfram, Joy (2020). Potential prophylactic and therapeutic effects of (hydroxy)chloroquine against SARS-CoV-2. Mayo Clinic Basic Science Mini-Symposium on COVID-19, Rochester, Minn, United States [virtual] , April 2020.
Gorelov, D., Di Florio, Damian, Salomon, G.R., Jain, A., Saikaili, N.E., Beetler, Danielle, Shrestha, S., Tian, Ming, Wolfram, Joy and Fairweather, DeLisa (2020). Regenerative medicine therapy: adipose derived extracellular vesicles in viral myocarditisRegenerative medicine therapy: adipose derived extracellular vesicles in viral myocarditis. 2020 Soars Virtual Conference, Jacksonville, FL, United States , April 2020.
Wolfram, Joy (2020). Synthetic and biological nanoparticles for cancer and inflammatory conditions. Nanoscience Seminar, New York, NY, United States, 27 March 2020. New York, NY, United States: City University of New York.
Wolfram, Joy (2020). TED TALK: the future of nanomedicine. Mayo Clinic Obstetrics/Gynecology Clinical and Surgical Updates: Staying Current and Ahead of the Curve 2020, Jacksonville, FL, United States , 17 February 2020. Jacksonville, FL, United States: Mayo Clinic.
Wolfram, Joy (2020). The magic of nanoparticles and cancer. Inspire2Live Annual Congress, Amsterdam, Netherlands , January 2020.
Iannotta, Dalila, Celia, Christian, Wolfram, Joy, Agata, P. and Di Marzio, Luisa (2020). Hybrid nanocarrier library based biomaterials for therapeutic applications. 1st International Northern Southern Europe Workshop in Nanomedicine, Chieti, Italy, January 2020.
Wolfram, Joy (2019). Extracellular vesicles for therapeutic and diagnostic use. Oslo Science Park Symposium in Molecular Medicine and Precision Medicine, Oslo, Norway , December 2019.
Wolfram, Joy (2019). Three emerging concepts in clinical nanomedicine. University of Washington, Seattle, WA USA, December 2019.
Wolfram, Joy (2019). Nanomedicine for cancer and beyond. Pharmatest Seminar Series, Turku, Finland, December 2019.
Wolfram, Joy (2019). Extracellular vesicles for therapeutic and diagnostic use. University of Pennsylvania Annual Symposium of the Center for Targeted Therapeutics and Translational Nanomedicine, Philadelphia, PA, United States, December 2019.
Wolfram, Joy (2019). Extracellular vesicle-based therapeutic and diagnostic strategies. Harvard University School of Engineering and Applied Sciences Seminar Series, Boston, MA, United States , November 2019.
Wolfram, Joy (2019). Three emerging concepts in clinical nanomedicine. Fralin Biomedical Research Institute, Roanoke, VA, United States , November 2019.
Wolfram, Joy (2019). How nanoparticles could change the way we treat cancer. TED, Global, October 2019.
Wolfram, Joy (2019). Diagnostic and therapeutic biogenic nanoparticles. Vall d'Hebron Research Institute Seminar Series, Barcelona, Spain , 10 September 2019.
Wolfram, Joy (2019). Education and outreach summary. Physical Sciences - Oncology Network Annual Meeting, Minneapolis, MN, United States , September 2019.
Busatto, Sara, Walker, Sierra A. and Wolfram, Joy (2019). Extracellular vesicles secreted from braintropic cells display distinct interactions with brain endothelial cells. The First International Society for Extracellular Vesicles and Metastasis Research Society Joint Extracellular Vesicle Conference Focused on Cancer, Nashville, TN, United States, August 2019.
Walker, Sierra A., Pham, Anthony, Busatto, Sara and Wolfram, Joy (2019). Open science success in community outreach. Sage Assembly: Open Science and the Role of Common Evidence, Seattle, WA, United States , July 2019.
Wolfram, Joy (2019). Education and outreach unit. National Cancer Institute Physical Sciences-Oncology Network Site Visit, Houston, TX, United States , May 2019.
Di Florio, Damian, Bruno, Katelyn, Hill, A.R., Tian, Ming, Wolfram, Joy and Fairweather, DeLisa (2019). Adipose extracellular vesicles derived from female lipoaspirate inhibit viral myocarditis: potential new therapy. Organization for the Study of Sex Differences (OSSD) Annual Meeting, Washington, DC, United States , May 2019.
Wolfram, Joy (2019).
Nanotherapeutics for cancer and regenerative medicine. University of Oulu Biocenter Oulu Day, Oulu, Finland, April 2019.
Wolfram, Joy (2019). Extracellular vesicles in breast cancer. Mayo Clinic Breast Cancer Retreat, Rochester, MN USA, April 2019.
Wolfram, Joy (2019). Bringing life science innovation to the clinic. Enventure, Houston, TX USA, April 2019.
Wolfram, Joy (2019). Extracellular vesicles as therapeutic and diagnostic agents. Center for Immunotherapeutic Transport Oncophysics Seminar Series, Houston, TX USA, April 2019.
Wolfram, Joy (2019). Three emerging concepts in clinical nanomedicine. Harvard Medical School Initiative for RNA Medicine Seminar Series, Boston, MA, United States , March 2019.
Wolfram, Joy (2019). Transitioning to independence: lessons learned. 8th Annual Texas Medical Center Postdoctoral Career Symposium, Houston, TX, United Sates , February 2019.
Wolfram, Joy (2019). A revolution at the nanoscale. Clay Chamber Technology Conference, Orange Park, FL, United States, February 2019.
Wolfram, Joy (2019). Nanomedicine and extracellular vesicles. Arizona State University Biodesign Institute Seminar Series, Tempe, AZ, United States, January 2019.
Wolfram, Joy (2018). Extracellular vesicle therapeutics. International Symposium on Molecular Imaging, Nanomedicine, and Biotherapeutics Delivery, Seongnam, South Korea, November 2018.
Wolfram, Joy (2018). Synthetic and biological nanotherapeutics. National University of Singapore Biomedical Institute for Global Health Research and Technology Seminar Series, Singapore, October 2018.
Wolfram, Joy (2018). Synthetic and biological nanotherapeutics. Hong Kong Baptist University Center for Cancer and Inflammation Research Seminar Series, Hong Kong, China , October 2018.
Wolfram, Joy (2018). Emerging concepts in clinical nanomedicine: hemodynamics, modulation of innate immunity, and extracellular vesicles. Korea Research Institute of Chemical Technology Seminar Series, DaeJeon, South Korea , October 2018.
Wolfram, Joy (2018). Synthetic and biological nanotherapeutics. National University of Singapore Biomedical Institute for Global Health Research and Technology Seminar Series, Singapore, October 2018.
Wolfram, Joy (2018). A revolution at the nanoscale. TEDxJacksonville, Jacksonville, FL, United States, October 2018.
Wolfram, Joy (2018). Education and outreach summary. Cancer Systems Biology Consortium and Physical Sciences – Oncology Network Annual Meeting, Bethesda, MD, United States , September 2018.
Wolfram, Joy (2018). Engineered extracellular vesicles for drug delivery to the brain. European and Global Summit for Clinical Nanomedicine and Targeted Medicine, Basel, Switzerland , September 2018.
Wolfram, Joy (2018). Emerging concepts in clinical nanomedicine: hemodynamics and modulation of innate immunity. Beilstein Workshop on Translational Trends in Medicine, Ruedesheim, Germany , September 2018.
Wolfram, Joy (2018). Synthetic and biological nanotherapeutics. University of Helsinki Faculty of Pharmacy Seminar Series, Helsinki, Finland , August 2018.
Wolfram, Joy (2018). Synthetic nanoparticles and extracellular vesicles for medical applications. Florida State University Biomedical Sciences Seminar Series, Tallahassee, FL, United States , August 2018.
Busatto, Sara and Wolfram, Joy (2018). Brain-tropic extracellular vesicles for treatment of brain tumors. New York Academy of Sciences Science, Technology, Engineering, and Mathematics (STEM) Exchange: Research and Career Symposium, New York City, NY, United States, August 2018.
Porter, V., Singh, S., Che, P., Busatto, Sara, Wolfram, Joy, Brisbois, E. and Seal, S. (2018). Nanoceria-integrated biopatch to accelerate wound healing. University of Central Florida Poster Session, Orlando, FL, United States , August 2018.
Nizzero, Sara, Li, Feng, Venuta, Alessandro, Zhang, Guodong, Borsoi, Carlotta, Wolfram, Joy, Mai, Junhua, Shen, Haifa, Li, Zheng, Blanco, Elvin and Ferrari, Mauro (2018). Abstract LB-019: empowering preclinical studies: a systematic and quantitative analysis of biodistribution methods to facilitate clinical translation of new drugs. AACR Annual Meeting 2018, Chicago, IL USA, 14-18 April 2018. Philadelphia, PA USA: American Association for Cancer Research. doi: 10.1158/1538-7445.am2018-lb-019
Wolfram, Joy (2018). My scientific journey. University of Oxford Inspiration Speaker Series, Oxford, United Kingdom, July 2018.
Wolfram, Joy (2018). Future of nanomedicine in the next year. NanoGagliato, Gagliato, Italy , July 2018.
Wolfram, Joy (2018). Synthetic and biological nanotherapeutics. Mayo Clinic Arizona Science of Medicine Seminar Series, Scottsdale, AZ, United States , June 2018.
Wolfram, Joy (2018). Optimizing nanoparticle interactions with macrophages and endothelial cells for improved site-specific delivery. Canadian Society for Pharmaceutical Sciences Annual Conference, Toronto, Canada , May 2018.
Wolfram, Joy (2018). Education and outreach unit. National Cancer Institute Physical Sciences-Oncology Network Site Visit, Houston, TX, United States , May 2018.
Wolfram, Joy (2018). Nanomedicine and extracellular vesicles. Mayo Clinic Transplant Center Grand Rounds, Rochester, Min, United States , March 2018.
Yankson, Kiera, Shukla, N., Patel, T. and Wolfram, Joy (2017). Biological nanoparticles for drug delivery to the brain. Annual Biomedical Research Conference for Minority Students, Phoenix, AZ, United States , November 2017.
Wolfram, Joy (2017). The future of nanomedicine. Hello Tomorrow Global Summit, Paris, France, October 2017.
Wolfram, Joy (2017). Modulating macrophage activity to improve nanoparticle biodistribution. 2nd Summer School of European and International Societies for Nanomedicine, Barcelona, Spain , September 2017.
Wolfram, Joy (2017). Nanomedicine and extracellular vesicles. ebraska Center for the Prevention of Obesity Diseases Seminar Series, Lincoln, NE, United States , September 2017.
Wolfram, Joy (2017). Nanomedicine and extracellular vesicles. Karolinska Institutet Seminar Series, Stockholm, Sweden, September 2017.
Wolfram, Joy (2017). The macrophage switch: improving nanoparticle biodistribution. European and Global Summit for Clinical Nanomedicine & Targeted Medicine, Basel, Switzerland , May 2017.
Wolfram, Joy (2017). Center for immunotherapeutic transport oncophysics. 2017 Sage Assembly: Mapping Open Research Ecosystems, Seattle, WA, United States , April 2017.
Nizzero, Sara, Litvinov, Sergey, Alexeev, Dmitry, Economides, Athena, Rosa, Enrica De, Wolfram, Joy, Koumoutsakos, Petros and Ferrari, Mauro (2017). Abstract B04: from modeling to in vivo tracking: a new platform for the design of delivery vectors that exploit tumor microfluidics. AACR Special Conference: Engineering and Physical Sciences in Oncology, Boston, MA USA, 25-28 June 2016. Philadelphia, PA USA: American Association for Cancer Research. doi: 10.1158/1538-7445.epso16-b04
Wolfram, Joy, Shen, Jianliang, Shen, Haifa and Ferrari, Mauro (2017). Porous silicon micropartciles for siRNA delivery. RNA Nanotechnology Gordon Research Conference, Ventura, CA, United States , January 2017.
Wolfram, Joy (2016). Comparison of strategies for avoiding nanoparticle uptake by the mononuclear phagocyte system (young investigator short talk). 7th Mayo Clinic Angiogenesis and Tumor Microenvironment Symposium, Amelia Island, FL, United States , November 2016.
Samuelsson, Emma, Nizzero, Sara, Blanco, Elvin, Shen, Haifa, Ferrari, Mauro and Wolfram, Joy (2016). Comparison of strategies for avoiding nanoparticle uptake by the mononuclear phagocyte system. 7th Mayo Clinic Angiogenesis and Tumor Microenvironment Symposium, Amelia Island, FL United States , November 2016.
Paolino, Donatella, Cosco, D., Cilurzo, F., Gaspari, M., Celia, Christian, Failla, P., Wolfram, Joy, Celano, M., Fresta, Massimo and Russo, D. (2016). TSH-nanoliposomes: a thyroid targeted nanomedicine. XXIII National Meeting on Medicinal Chemistry, Fisciano, Italy , September 2015.
Wolfram, Joy (2016). Super stealth liposomes for drug delivery. European and Global Summit for Clinical Nanomedicine and Targeted Medicine, Basel, Switzerland , June 2016.
Wolfram, Joy (2016). Multistage delivery of siRNA. European Summit for Clinical Nanomedicine and Targeted Medicine, Basel, Switzerland , June 2016.
Celia, Christian, Huang, Y., Paolino, Donatella, Cosco, D., Wolfram, Joy, Di Marzio, Luisa, Cilurzo, F., Cristiano, M. C., Shen, Haifa and Fresta, Massimo (2016). Nanoliposomes as multidrug therapy for anticancer treatment. 10th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Glasgow, United Kingdom, April 2016.
Celia, Christian, Di Francesco, M., Locatelli, M., Cilurzo, F., Ventura, C. A., Wolfram, Joy, Carafa, M., Cristiano, M. C., Britti, D., Di Marzio, Luisa, Paolino, Donatella and Morittu, V. (2015). Nanoformulations of bergamot essential oil for in vitro anti neuroblastoma treatment. XXV Congresso Nazionale della Divisione di Chimica Analitica della Società Chimica Italiana, Trieste, Italy , September 2015.
Wolfram, Joy (2015). Porous silicon microparticles for the delivery of siRNA. University of Helsinki Faculty of Pharmacy Seminar Series, Helsinki, Finland , June 2015.
Cilurzo, F., Paolino, Donatella, Cosco, D., Gaspari, M., Celano, M., Wolfram, Joy, Cristiano, M. C., Filetti, S., Celia, Christian, Ferrari, Mauro and Fresta, Massimo (2015). TSH-PEGylated nanoliposomes for the efficacious thyroid targeting. Fourth International Conference: Frontiers in Polymer Science, Riva del Garda, Italy , May 2015.
Wolfram, Joy (2014). The nano-bio interface. Mini-Workshop for Nanosystems and Health Science, Catanzaro, Italy, July 2014.
Wolfram, Joy (2014). Shrinkage of pegylated and non-pegylated liposomes in serum. European Summit for Clinical Nanomedicine and Targeted Medicine, Basel, Switzerland , June 2014.
Wolfram, Joy, Yang, Yong, Celia, Christian, Shen, Haifa, Zhao, Yuliang and Ferrari, Mauro (2014). Shrinkage of pegylated and non-pegylated liposomes in serum. NanoBio-Europe: International Congress & Exhibition on Nanobiotechnology, Münster, Germany , June 2014.
Celia, Christian, Trapasso, E., Locatelli, M., Cosco, D., Ventura, C. A., Wolfram, Joy, Carafa, M., Di Marzio, Luisa and Paolino, Donatella (2014). Bergamot essential oil (BEO)-loaded liposomes: nanoformulation for anticancer activity on neuroblastoma cells. 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Lisbon, Portugal , April 2014.
Wolfram, Joy, Celia, Christian, Borsoi, Carlotta, Moten, Asad, Paolino, Donatella, Fresta, Massimo, Shen, Haifa, Ferrari, Mauro, Di Marzio, Luisa and Carafa, M. (2014). Celastrol-loaded liposomes as nano-drugs for the potential treatment of prostate cancer. 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Lisbon, Portugal , April 2014.
Yang, Yong, Wolfram, Joy, Shen, Haifa, Fang, X. and Ferrari, Mauro (2013). Polyarginine induces an antitumor immune response through binding to toll-like receptor 4 (TLR4). ChinaNano2013: International Conference on Nanoscience and Technology, Beijing, China, September 2013.
Wolfram, Joy, Ferrari, Mauro and Zhao, Yuliang (2013). Joint collaboration between the National Center for Nanoscience and Technology (NCNST) and the Houston Methodist Hospital. ChinaNano2013: International Conference on Nanoscience and Technology, Beijing, China , September 2013.
Koay, Eugene, Kirui, Dickson, Yang, Yubo, Wolfram, Joy, Shen, Haifa and Ferrari, Mauro (2012). Toward understanding and overcoming multiscale mass transport differentials in cancer. Third Annual Physical Sciences – Oncology Centers (PS-OCs) Investigators Meeting, Tampa, FL United States , April 2012.
Wolfram, Joy, Mojallal, M., Zheng, Y. and Holmgren, L. (2009). Angiomotin-like protein 2 (AmotL2), a potential target for cancer therapy. Amgen Scholars Symposium, Cambridge, United Kingdom, September 2009.
Newspaper Article
Wolfram, Joy (2024, 09 24). Student caps will hit research Australian Financial Review