Researcher biography
Joy Wolfram leads a nanomedicine and extracellular vesicle research laboratory with the goal of developing innovative approaches that bring the next generation of treatments and diagnostics directly to the clinic. Her research program has three main focus areas: 1) develop improved methods for extracellular vesicle isolation from human biofluids, 2) design hybrid drug delivery systems consisting of extracellular vesicles fused with synthetic nanoparticles for a 'best-of-both-worlds' approach, and 3) understand the role of extracellular vesicles in breast cancer metastasis.
Book Chapters
Borsoi, Carlotta, Wolfram, Joy and Ferrari, Mauro (2016). Nanomedicine Activities in the United States and Worldwide. Nanoscience and Nanotechnology for Human Health. (pp. 21-50) Weinheim, Germany: wiley. doi: 10.1002/9783527692057.ch3
Suri, Krishna, Wolfram, Joy, Shen, Haifa and Ferrari, Mauro (2015). Advances in Nanotechnology-Based Drug Delivery Platforms and Novel Drug Delivery Systems. Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies. (pp. 41-58) Elsevier Inc.. doi: 10.1016/B978-0-12-416603-5.00003-1
Journal Articles
Busatto, Sara, Yang, Yubo, Iannotta, Dalila, Davidovich, Irina, Talmon, Yeshayahu and Wolfram, Joy (2022). Considerations for extracellular vesicle and lipoprotein interactions in cell culture assays. Journal of Extracellular Vesicles, 11 (4) e12202, e12202. doi: 10.1002/jev2.12202
Yang, Man, Walker, Sierra A., Aguilar Díaz de León, Jesús S., Davidovich, Irina, Broad, Kelly, Talmon, Yeshayahu, Borges, Chad R. and Wolfram, Joy (2022). Extracellular vesicle glucose transporter-1 and glycan features in monocyte-endothelial inflammatory interactions. Nanomedicine, 42 102515, 102515. doi: 10.1016/j.nano.2022.102515
Wang, Xinghua, Pham, Anthony, Kang, Lu, Walker, Sierra A., Davidovich, Irina, Iannotta, Dalila, Terkonda, Sarvam P., Shapiro, Shane, Talmon, Yeshayahu, Pham, Si and Wolfram, Joy (2022). Effects of adipose-derived biogenic nanoparticle-associated microrna-451a on toll-like receptor 4-induced cytokines. Pharmaceutics, 14 (1) 16, 16. doi: 10.3390/pharmaceutics14010016
Iannotta, Dalila, Yang, Man, Celia, Christian, Di Marzio, Luisa and Wolfram, Joy (2021). Extracellular vesicle therapeutics from plasma and adipose tissue. Nano Today, 39 101159, 101159. doi: 10.1016/j.nantod.2021.101159
Busatto, Sara, Iannotta, Dalila, Walker, Sierra A., Di Marzio, Luisa and Wolfram, Joy (2021). A simple and quick method for loading proteins in extracellular vesicles. Pharmaceuticals, 14 (4) 356, 356. doi: 10.3390/ph14040356
Hu, Tony, Wolfram, Joy and Srivastava, Sudhir (2021). Extracellular vesicles in cancer detection: hopes and hypes. Trends in Cancer, 7 (2), 122-133. doi: 10.1016/j.trecan.2020.09.003
Witwer, Kenneth W. and Wolfram, Joy (2021). Extracellular vesicles versus synthetic nanoparticles for drug delivery. Nature Reviews Materials, 6 (2), 103-106. doi: 10.1038/s41578-020-00277-6
Walker, Sierra A., Pham, Anthony, Nizzero, Sara, Kim, Mingee, Riter, Bob, Bletz, Julie, Judge, Sheila, Phillips, Benette, Noble, Dorottya, Murray, Diana, Wetzel, Erin, Samson, Susan, McMahon, Mariah, Flink, Carl, Couch, Jennifer, Tomlin, Claire, Swanson, Kristin, Anderson, Alexander R. A., Odde, David, Shen, Haifa, Hughes, Shannon, Zahir, Nastaran, Enderling, Heiko and Wolfram, Joy (2021). Education and outreach in physical sciences in oncology. Trends in Cancer, 7 (1), 3-9. doi: 10.1016/j.trecan.2020.10.007
Ali, Mojahid, Pham, Anthony, Wang, Xinghua, Wolfram, Joy and Pham, Si (2020). Extracellular vesicles for treatment of solid organ ischemia-reperfusion injury. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 20 (12), 3294-3307. doi: 10.1111/ajt.16164
Busatto, Sara, Yang, Yubo, Walker, Sierra A., Davidovich, Irina, Lin, Wan-Hsin, Lewis-Tuffin, Laura, Anastasiadis, Panagiotis Z., Sarkaria, Jann, Talmon, Yeshayahu, Wurtz, Gregory and Wolfram, Joy (2020). Brain metastases-derived extracellular vesicles induce binding and aggregation of low-density lipoprotein. Journal of Nanobiotechnology, 18 (1) 162, 162. doi: 10.1186/s12951-020-00722-2
Walker, Sierra A., Aguilar Díaz De León, Jesús S., Busatto, Sara, Wurtz, Gregory A., Zubair, Abba C., Borges, Chad R. and Wolfram, Joy (2020). Glycan node analysis of plasma-derived extracellular vesicles. Cells, 9 (9), 1946. doi: 10.3390/cells9091946
Busatto, Sara, Walker, Sierra A., Grayson, Whisper, Pham, Anthony, Tian, Ming, Nesto, Nicole, Barklund, Jacqueline and Wolfram, Joy (2020). Lipoprotein-based drug delivery. Advanced drug delivery reviews, 159, 377-390. doi: 10.1016/j.addr.2020.08.003
Hu, Tony Y., Frieman, Matthew and Wolfram, Joy (2020). Insights from nanomedicine into chloroquine efficacy against COVID-19. Nature Nanotechnology, 15 (4), 247-249. doi: 10.1038/s41565-020-0674-9
Tian, Ming, Ticer, Taylor, Wang, Qikun, Walker, Sierra, Pham, Anthony, Suh, Annie, Busatto, Sara, Davidovich, Irina, Al-Kharboosh, Rawan, Lewis-Tuffin, Laura, Ji, Baoan, Quinones-Hinojosa, Alfredo, Talmon, Yeshayahu, Shapiro, Shane, Rueckert, Felix and Wolfram, Joy (2020). Adipose-derived biogenic nanoparticles for suppression of inflammation. Small, 16 (10) 1904064, 1-13. doi: 10.1002/smll.201904064
Martins, João Pedro, das Neves, José, de la Fuente, María, Celia, Christian, Florindo, Helena, Günday-Türeli, Nazende, Popat, Amirali, Santos, José Luis, Sousa, Flávia, Schmid, Ruth, Wolfram, Joy, Sarmento, Bruno and Santos, Hélder A. (2020). The solid progress of nanomedicine. Drug Delivery and Translational Research, 10 (3), 726-729. doi: 10.1007/s13346-020-00743-2
Walker, Sierra, Busatto, Sara, Pham, Anthony, Tian, Ming, Suh, Annie, Carson, Kelsey, Quintero, Astrid, Lafrence, Maria, Malik, Hanna, Santana, Moises X and Wolfram, Joy (2019). Extracellular vesicle-based drug delivery systems for cancer treatment. Theranostics, 9 (26), 8001-8017. doi: 10.7150/thno.37097
Nizzero, Sara, Li, Feng, Zhang, Guodong, Venuta, Alessandro, Borsoi, Carlotta, Mai, Junhua, Shen, Haifa, Wolfram, Joy, Li, Zheng, Blanco, Elvin and Ferrari, Mauro (2019). Systematic comparison of methods for determining the in vivo biodistribution of porous nanostructured injectable inorganic particles. Acta Biomaterialia, 97, 501-512. doi: 10.1016/j.actbio.2019.08.002
Leong, Hon S., Butler, Kimberly S., Brinker, C. Jeffrey, Azzawi, May, Conlan, Steve, Dufès, Christine, Owen, Andrew, Rannard, Steve, Scott, Chris, Chen, Chunying, Dobrovolskaia, Marina A., Kozlov, Serguei V., Prina-Mello, Adriele, Schmid, Ruth, Wick, Peter, Caputo, Fanny, Boisseau, Patrick, Crist, Rachael M., McNeil, Scott E., Fadeel, Bengt, Tran, Lang, Hansen, Steffen Foss, Hartmann, Nanna B., Clausen, Lauge P. W., Skjolding, Lars M., Baun, Anders, Ågerstrand, Marlene, Gu, Zhen, Lamprou, Dimitrios A. ... Pastore, Chiara (2019). Publisher Correction: On the issue of transparency and reproducibility in nanomedicine (Nature Nanotechnology, (2019), 14, 7, (629-635), 10.1038/s41565-019-0496-9). Nature Nanotechnology, 14 (9). doi: 10.1038/s41565-019-0538-3
Suh, Annie, Pham, Anthony, Cress, Mikel Jean, Pincelli, Thais, TerKonda, Sarvam P., Bruce, Alison J., Zubair, Abba C., Wolfram, Joy and Shapiro, Shane A. (2019). Adipose-derived cellular and cell-derived regenerative therapies in dermatology and aesthetic rejuvenation. Ageing Research Reviews, 54 100933. doi: 10.1016/j.arr.2019.100933
Leong, Hon S., Butler, Kimberly S., Brinker, C. Jeffrey, Azzawi, May, Conlan, Steve, Dufès, Christine, Owen, Andrew, Rannard, Steve, Scott, Chris, Chen, Chunying, Dobrovolskaia, Marina A., Kozlov, Serguei V., Prina-Mello, Adriele, Schmid, Ruth, Wick, Peter, Caputo, Fanny, Boisseau, Patrick, Crist, Rachael M., McNeil, Scott E., Fadeel, Bengt, Tran, Lang, Hansen, Steffen Foss, Hartmann, Nanna B., Clausen, Lauge P. W., Skjolding, Lars M., Baun, Anders, Ågerstrand, Marlene, Gu, Zhen, Lamprou, Dimitrios A. ... Pastore, Chiara (2019). Publisher Correction: On the issue of transparency and reproducibility in nanomedicine (Nature Nanotechnology, (2019), 14, 7, (629-635), 10.1038/s41565-019-0496-9). Nature Nanotechnology, 14 (8). doi: 10.1038/s41565-019-0523-x
Leong, Hon S., Butler, Kimberly S., Brinker, C. Jeffrey, Azzawi, May, Conlan, Steve, Dufés, Christine, Owen, Andrew, Rannard, Steve, Scott, Chris, Chen, Chunying, Dobrovolskaia, Marina A., Kozlov, Serguei V., Prina-Mello, Adriele, Schmid, Ruth, Wick, Peter, Caputo, Fanny, Boisseau, Patrick, Crist, Rachael M., McNeil, Scott E., Fadeel, Bengt, Tran, Lang, Hansen, Steffen Foss, Hartmann, Nanna B., Clausen, Lauge P. W., Skjolding, Lars M., Baun, Anders, Ågerstrand, Marlene, Gu, Zhen, Lamprou, Dimitrios A. ... Pastore, Chiara (2019). On the issue of transparency and reproducibility in nanomedicine. Nature Nanotechnology, 14 (7), 629-635. doi: 10.1038/s41565-019-0496-9
Busatto, Sara, Pham, Anthony, Suh, Annie, Shapiro, Shane and Wolfram, Joy (2019). Organotropic drug delivery: Synthetic nanoparticles and extracellular vesicles. Biomedical Microdevices, 21 (2) 46, 46. doi: 10.1007/s10544-019-0396-7
Wolfram, Joy and Ferrari, Mauro (2019). Clinical cancer nanomedicine. Nano Today, 25, 85-98. doi: 10.1016/j.nantod.2019.02.005
Busatto, Sara, Vilanilam, George, Ticer, Taylor, Lin, Wen-Lang, Dickson, Dennis, Shapiro, Shane, Bergese, Paolo and Wolfram, Joy (2018). Tangential flow filtration for highly efficient concentration of extracellular vesicles from large volumes of fluid. Cells, 7 (12), 273. doi: 10.3390/cells7120273
Thery, Clotilde, Witwer, Kenneth W., Aikawa, Elena, Jose Alcaraz, Maria, Anderson, Johnathon D., Andriantsitohaina, Ramaroson, Antoniou, Anna, Arab, Tanina, Archer, Fabienne, Atkin-Smith, Georgia K., Ayre, D. Craig, Bach, Jean-Marie, Bachurski, Daniel, Baharvand, Hossein, Balaj, Leonora, Baldacchino, Shawn, Bauer, Natalie N., Baxter, Amy A., Bebawy, Mary, Beckham, Carla, Zavec, Apolonija Bedina, Benmoussa, Abderrahim, Berardi, Anna C., Bergese, Paolo, Bielska, Ewa, Blenkiron, Cherie, Bobis-Wozowicz, Sylwia, Boilard, Eric, Boireau, Wilfrid ... Zuba-Surma, Ewa K. (2018). Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. Journal of Extracellular Vesicles, 7 (1) 1535750, 1535750. doi: 10.1080/20013078.2018.1535750
Pelt, Joe, Busatto, Sara, Ferrari, Mauro, Thompson, E. Aubrey, Mody, Kabir and Wolfram, Joy (2018). Chloroquine and nanoparticle drug delivery: A promising combination. Pharmacology and Therapeutics, 191, 43-49. doi: 10.1016/j.pharmthera.2018.06.007
Mu, Chaofeng, Wu, Xiaoyan, Zhou, Xinyu, Wolfram, Joy, Shen, Jianliang, Zhang, Dechen, Mai, Junhua, Xia, Xiaojun, Holder, Ashley M., Ferrari, Mauro, Liu, Xuewu and Shen, Haifa (2018). Chemotherapy sensitizes therapy-resistant cells to mild hyperthermia by suppressing heat shock protein 27 expression in triple-negative breast cancer. Clinical Cancer Research, 24 (19), 4900-4912. doi: 10.1158/1078-0432.CCR-17-3872
Borrelli, David A., Yankson, Kiera, Shukla, Neha, Vilanilam, George, Ticer, Taylor and Wolfram, Joy (2018). Extracellular vesicle therapeutics for liver disease. Journal of Controlled Release, 273, 86-98. doi: 10.1016/j.jconrel.2018.01.022
Liu, Haoran, Mai, Junhua, Shen, Jianliang, Wolfram, Joy, Li, Zhaoqi, Zhang, Guodong, Xu, Rong, Li, Yan, Mu, Chaofeng, Zu, Youli, Li, Xin, Lokesh, Ganesh L., Thiviyanathan, Varatharasa, Volk, David E., Gorenstein, David G., Ferrari, Mauro, Hu, Zhongbo and Shen, Haifa (2018). A novel DNA aptamer for dual targeting of polymorphonuclear myeloid-derived suppressor cells and tumor cells. Theranostics, 8 (1), 31-44. doi: 10.7150/thno.21342
Wolfram, Joy, Nizzero, Sara, Liu, Haoran, Li, Feng, Zhang, Guodong, Li, Zheng, Shen, Haifa, Blanco, Elvin and Ferrari, Mauro (2017). A chloroquine-induced macrophage-preconditioning strategy for improved nanodelivery. Scientific Reports, 7 (1) 13738. doi: 10.1038/s41598-017-14221-2
Samuelsson, Emma, Shen, Haifa, Blanco, Elvin, Ferrari, Mauro and Wolfram, Joy (2017). Contribution of Kupffer cells to liposome accumulation in the liver. Colloids and Surfaces B: Biointerfaces, 158, 356-362. doi: 10.1016/j.colsurfb.2017.07.014
Khalid, Ayesha, Persano, Stefano, Shen, Haifa, Zhao, Yuliang, Blanco, Elvin, Ferrari, Mauro and Wolfram, Joy (2017). Strategies for improving drug delivery: nanocarriers and microenvironmental priming. Expert Opinion on Drug Delivery, 14 (7), 865-877. doi: 10.1080/17425247.2017.1243527
Shen, Jianliang, Kim, Han-Cheon, Wolfram, Joy, Mu, Chaofeng, Zhang, Wei, Liu, Haoran, Xie, Yan, Mai, Junhua, Zhang, Hang, Li, Zhi, Guevara, Maria, Mao, Zong-Wan and Shen, Haifa (2017). A liposome encapsulated ruthenium polypyridine complex as a theranostic platform for triple-negative breast cancer. Nano Letters, 17 (5), 2913-2920. doi: 10.1021/acs.nanolett.7b00132
Shen, Jianliang, Liu, Haoran, Mu, Chaofeng, Wolfram, Joy, Zhang, Wei, Kim, Han-Cheon, Zhu, Guixian, Hu, Zhongbo, Ji, Liang-Nian, Liu, Xuewu, Ferrari, Mauro, Mao, Zong-Wan and Shen, Haifa (2017). Multi-step encapsulation of chemotherapy and gene silencing agents in functionalized mesoporous silica nanoparticles. Nanoscale, 9 (16), 5329-5341. doi: 10.1039/c7nr00377c
Shen, Jianliang, Wolfram, Joy, Ferrari, Mauro and Shen, Haifa (2017). Taking the vehicle out of drug delivery. Materials Today, 20 (3), 95-97. doi: 10.1016/j.mattod.2017.01.013
Venuta, Alessandro, Wolfram, Joy, Shen, Haifa and Ferrari, Mauro (2017). Post-nano strategies for drug delivery: multistage porous silicon microvectors. Journal of Materials Chemistry B, 5 (2), 207-219. doi: 10.1039/C6TB01978A
Mi, Yu, Wolfram, Joy, Mu, Chaofeng, Liu, Xuewu, Blanco, Elvin, Shen, Haifa and Ferrari, Mauro (2016). Enzyme-responsive multistage vector for drug delivery to tumor tissue. Pharmacological Research, 113, 92-99. doi: 10.1016/j.phrs.2016.08.024
Persano, Stefano, Guevara, Maria L., Wolfram, Joy, Blanco, Elvin, Shen, Haifa, Ferrari, Mauro and Pompa, Pier Paolo (2016). Label-free isothermal amplification assay for specific and highly sensitive colorimetric miRNA detection. ACS Omega, 1 (3), 448-455. doi: 10.1021/acsomega.6b00109
Scott, Bronwyn, Shen, Jianliang, Nizzero, Sara, Boom, Kathryn, Persano, Stefano, Mi, Yu, Liu, Xuewu, Zhao, Yuliang, Blanco, Elvin, Shen, Haifa, Ferrari, Mauro and Wolfram, Joy (2016). A pyruvate decarboxylase-mediated therapeutic strategy for mimicking yeast metabolism in cancer cells. Pharmacological Research, 111, 413-421. doi: 10.1016/j.phrs.2016.07.005
Wolfram, Joy, Scott, Bronwyn, Boom, Kathryn, Shen, Jianliang, Borsoi, Carlotta, Suri, Krishna, Grande, Rossella, Fresta, Massimo, Celia, Christian, Zhao, Yuliang, Shen, Haifa and Ferrari, Mauro (2016). Hesperetin liposomes for cancer therapy. Current Drug Delivery, 13 (5), 711-719. doi: 10.2174/1567201812666151027142412
Mi, Yu, Mu, Chaofeng, Wolfram, Joy, Deng, Zaian, Hu, Tony Ye, Liu, Xuewu, Blanco, Elvin, Shen, Haifa and Ferrari, Mauro (2016). A micro/nano composite for combination treatment of melanoma lung metastasis. Advanced Healthcare Materials, 5 (8), 936-946. doi: 10.1002/adhm.201500910
Wolfram, Joy, Shen, Haifa and Ferrari, Mauro (2015). Multistage vector (MSV) therapeutics. Journal of Controlled Release, 219, 406-415. doi: 10.1016/j.jconrel.2015.08.010
Scavo, Maria Principia, Gentile, Emanuela, Wolfram, Joy, Gu, Jianhua, Barone, Michele, Evangelopoulos, Michael, Martinez, Jonathan O., Liu, Xuewu, Celia, Christian, Tasciotti, Ennio, Vilar, Eduardo and Shen, Haifa (2015). Multistage vector delivery of sulindac and silymarin for prevention of colon cancer. Colloids and Surfaces B: Biointerfaces, 136, 694-703. doi: 10.1016/j.colsurfb.2015.10.005
Khalid, Ayesha, Wolfram, Joy, Ferrari, Ilaria, Mu, Chaofeng, Mai, Junhua, Yang, Zhizhou, Zhao, Yuliang, Ferrari, Mauro, Ma, Xiaojing and Shen, Haifa (2015). Recent advances in discovering the role of CCL5 in metastatic breast cancer. Mini-Reviews in Medicinal Chemistry, 15 (13), 1063-1072. doi: 10.2174/138955751513150923094709
Yang, Zhizhou, Sun, Zhaorui, Liu, Hongmei, Ren, Yi, Shao, Danbing, Zhang, Wei, Lin, Jinfeng, Wolfram, Joy, Wang, Feng and Nie, Shinan (2015). Connective tissue growth factor stimulates the proliferation, migration and differentiation of lung fibroblasts during paraquat-induced pulmonary fibrosis. Molecular Medicine Reports, 12 (1), 1091-1097. doi: 10.3892/mmr.2015.3537
Lin, Jinfeng, Sun, Zhaorui, Zhang, Wei, Liu, Hongmei, Shao, Danbing, Ren, Yi, Wen, Yanfang, Cao, Liping, Wolfram, Joy, Yang, Zhizhou and Nie, Shinan (2015). Protective effects of intestinal trefoil factor (ITF) on gastric mucosal epithelium through activation of extracellular signal-regulated kinase 1/2 (ERK1/2). Molecular and Cellular Biochemistry: an international journal for chemical biology in health and disease, 404 (1-2), 263-270. doi: 10.1007/s11010-015-2386-2
Pasut, Gianfranco, Paolino, Donatella, Celia, Christian, Mero, Anna, Joseph, Adrian Steve, Wolfram, Joy, Cosco, Donato, Schiavon, Oddone, Shen, Haifa and Fresta, Massimo (2015). Polyethylene glycol (PEG)-dendron phospholipids as innovative constructs for the preparation of super stealth liposomes for anticancer therapy. Journal of Controlled Release, 199, 106-113. doi: 10.1016/j.jconrel.2014.12.008
Shen, Jianliang, Wu, Xiaoyan, Lee, Yeonju, Wolfram, Joy, Yang, Zhizhou, Mao, Zong-Wan, Ferrari, Mauro and Shen, Haifa (2015). Porous silicon microparticles for delivery of siRNA therapeutics. Journal of Visualized Experiments (95) e52075. doi: 10.3791/52075
Wolfram, Joy, Zhu, Motao, Yang, Yong, Shen, Jianliang, Gentile, Emanuela, Paolino, Donatella, Fresta, Massimo, Nie, Guangjun, Chen, Chunying, Shen, Haifa, Ferrari, Mauro and Zhao, Yuliang (2015). Safety of nanoparticles in medicine. Current Drug Targets, 16 (14), 1671-1681. doi: 10.2174/1389450115666140804124808
Wolfram, Joy, Yang, Yong, Shen, Jianliang, Moten, Asad, Chen, Chunying, Shen, Haifa, Ferrari, Mauro and Zhao, Yuliang (2014). The nano-plasma interface: Implications of the protein corona. Colloids and Surfaces B: Biointerfaces, 124, 17-24. doi: 10.1016/j.colsurfb.2014.02.035
Shen, Jianliang, Kim, Han-Cheon, Mu, Chaofeng, Gentile, Emanuela, Mai, Junhua, Wolfram, Joy, Ji, Liang-Nian, Ferrari, Mauro, Mao, Zong-wan and Shen, Haifa (2014). Multifunctional gold nanorods for siRNA gene silencing and photothermal therapy. Advanced Healthcare Materials, 3 (10), 1629-1637. doi: 10.1002/adhm.201400103
Jiang, Xionghua, Chen, Zhenxing, Wolfram, Joy, Wei, Zhongxian, Shen, Yuqiu and Yang, Zhizhou (2014). The impact of lubricants on the precision lapping process. Microscopy and Microanalysis, 20 (6), 1708-1714. doi: 10.1017/S1431927614013397
Yang, Yong, Wolfram, Joy, Fang, Xiaohong, Shen, Haifa and Ferrari, Mauro (2014). Polyarginine induces an antitumor immune response through binding to toll-like receptor 4. Small, 10 (7), 1250-1254. doi: 10.1002/smll.201302887
Wolfram, Joy, Suri, Krishna, Yang, Yong, Shen, Jianliang, Celia, Christian, Fresta, Massimo, Zhao, Yuliang, Shen, Haifa and Ferrari, Mauro (2014). Shrinkage of pegylated and non-pegylated liposomes in serum. Colloids and Surfaces B: Biointerfaces, 114, 294-300. doi: 10.1016/j.colsurfb.2013.10.009
Rauhamäki, Virve, Wolfram, Joy, Jokitalo, Eija, Hanski, Ilkka and Dahlhoff, Elizabeth P. (2014). Differences in the aerobic capacity of flight muscles between butterfly populations and species with dissimilar flight abilities. PLoS ONE, 9 (1) e78069, e78069. doi: 10.1371/journal.pone.0078069
Wolfram, Joy, Zhu, Motao, Yang, Yong, Shen, Jianliang, Gentile, Emanuela, Paolino, Donatella, Fresta, Massimo, Nie, Guangjun, Chen, Chunying, Shen, Haifa, Ferrari, Mauro and Zhao, Yuliang (2014). Safety of nanoparticles in medicine. Current Drug Targets, 15 (10) A001.
Shen, Jianliang, Kim, Han-Cheon, Su, Hua, Wang, Feng, Wolfram, Joy, Kirui, Dickson, Mai, Junhua, Mu, Chaofeng, Ji, Liang-Nian, Mao, Zong-Wan and Shen, Haifa (2014). Cyclodextrin and polyethylenimine functionalized mesoporous silica nanoparticles for delivery of siRNA cancer therapeutics. Theranostics, 4 (5), 487-497. doi: 10.7150/thno.8263
Jiang, Xionghua, Chen, Zhenxing, Wolfram, Joy and Yang, Zhizhou (2014). Mechanistic features of nanodiamonds in the lapping of magnetic heads. Scientific World Journal, 2014 326427. doi: 10.1155/2014/326427
Wolfram, Joy, Suri, Krishna, Huang, Yi, Molinaro, Roberto, Borsoi, Carlotta, Scott, Bronwyn, Boom, Kathryn, Paolino, Donatella, Fresta, Massimo, Wang, Jianghua, Ferrari, Mauro, Celia, Christian and Shen, Haifa (2014). Evaluation of anticancer activity of celastrol liposomes in prostate cancer cells. Journal of Microencapsulation, 31 (5), 501-507. doi: 10.3109/02652048.2013.879932
Paolino, Donatella, Cosco, Donato, Gaspari, Marco, Celano, Marilena, Wolfram, Joy, Voce, Pasquale, Puxeddu, Efisio, Filetti, Sebastiano, Celia, Christian, Ferrari, Mauro, Russo, Diego and Fresta, Massimo (2014). Targeting the thyroid gland with thyroid-stimulating hormone (TSH)-nanoliposomes. Biomaterials, 35 (25), 7101-7109. doi: 10.1016/j.biomaterials.2014.04.088
Yang, Yong, Wolfram, Joy, Shen, Jianliang, Zhao, Yuliang, Fang, Xiaohong, Shen, Haifa and Ferrari, Mauro (2013). Live-cell single-molecule imaging reveals clathrin and caveolin-1 dependent docking of SMAD4 at the cell membrane. FEBS Letters, 587 (24), 3912-3920. doi: 10.1016/j.febslet.2013.10.041
Gentile, Emanuela, Cilurzo, Felisa, Di Marzio, Luisa, Carafa, Maria, Ventura, Cinzia Anna, Wolfram, Joy, Paolino, Donatella and Celia, Christian (2013). Liposomal chemotherapeutics. Future Oncology, 9 (12), 1849-1859. doi: 10.2217/FON.13.146
Celia, Christian, Trapasso, Elena, Locatelli, Marcello, Navarra, Michele, Ventura, Cinzia Anna, Wolfram, Joy, Carafa, Maria, Morittu, Valeria Maria, Britti, Domenico, Di Marzio, Luisa and Paolino, Donatella (2013). Anticancer activity of liposomal bergamot essential oil (BEO) on human neuroblastoma cells. Colloids and Surfaces B: Biointerfaces, 112, 548-553. doi: 10.1016/j.colsurfb.2013.09.017
Shen, Jianliang, Xu, Rong, Mai, Junhua, Kim, Han-Cheon, Guo, Xiaojing, Qin, Guoting, Yang, Yong, Wolfram, Joy, Mu, Chaofeng, Xia, Xiaojun, Gu, Jianhua, Liu, Xuewu, Mao, Zong-Wan, Ferrari, Mauro and Shen, Haifa (2013). High capacity nanoporous silicon carrier for systemic delivery of gene silencing therapeutics. ACS Nano, 7 (11), 9867-9880. doi: 10.1021/nn4035316
Yang, Yong, Wolfram, Joy, Boom, Kathryn, Fang, Xiaohong, Shen, Haifa and Ferrari, Mauro (2013). Hesperetin impairs glucose uptake and inhibits proliferation of breast cancer cells. Cell Biochemistry and Function, 31 (5), 374-379. doi: 10.1002/cbf.2905
Molinaro, Roberto, Wolfram, Joy, Federico, Cinzia, Cilurzo, Felisa, Di Marzio, Luisa, Ventura, Cinzia A., Carafa, Maria, Celia, Christian and Fresta, Massimo (2013). Polyethylenimine and chitosan carriers for the delivery of RNA interference effectors. Expert Opinion on Drug Delivery, 10 (12), 1653-1668. doi: 10.1517/17425247.2013.840286
Yang, Yong, Wolfram, Joy, Shen, Haifa, Fang, Xiaohong and Ferrari, Mauro (2012). Hesperetin: An inhibitor of the transforming growth factor-β (TGF-β) signaling pathway. European Journal of Medicinal Chemistry, 58, 390-395. doi: 10.1016/j.ejmech.2012.10.028
Conference Papers
Conley, S. M., Bian, X., Gowan, C. C., Snow, Z. K., Smith, A. L., Lerman, L., Wolfram, J. V., Zubair, A. and Hickson, L. (2021). SYSTEMIC DELIVERY OF HUMAN BONE-MARROW DERIVED EXTRACELLULAR VESICLES AMELIORATES KIDNEY INJURY AND INFLAMMATION IN AN ACCELERATED DIABETIC KIDNEY DISEASE MOUSE MODEL. OXFORD: ELSEVIER SCI LTD.
Conley, S.M., Bian, X., C. Gowan, C., Snow, Z.K., Smith, A.L., Lerman, L., Wolfram, J.V., Zubair, A. and Hickson, L. (2021). Systemic delivery of human bone-marrow derived extracellular vesicles ameliorates kidney injury and inflammation in an accelerated diabetic kidney disease mouse model. 27th Annual ISCT Meeting, Online, 25 - 28 May 2021. Oxford, United Kingdom: Elsevier. doi: 10.1016/s1465324921004448
Nizzero, Sara, Li, Feng, Venuta, Alessandro, Zhang, Guodong, Borsoi, Carlotta, Wolfram, Joy, Mai, Junhua, Shen, Haifa, Li, Zheng, Blanco, Elvin and Ferrari, Mauro (2018). Abstract LB-019: empowering preclinical studies: a systematic and quantitative analysis of biodistribution methods to facilitate clinical translation of new drugs. AACR Annual Meeting 2018, Chicago, IL USA, 14-18 April 2018. Philadelphia, PA USA: American Association for Cancer Research. doi: 10.1158/1538-7445.am2018-lb-019
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